ArticleInternational journal of molecular sciences2024
Synthesis of Pyrazole-Based Inhibitors of the Bacterial Enzyme
Thomas DiPuma, Emma H Kelley, Teerana Thabthimthong, Alayna Bland, Katherine Konczak, Katherine J Torma, Thahani S Habeeb Mohammad, Kenneth W Olsen, Daniel P Becker
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In one paragraphArticle in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
Thomas DiPumaDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.ORCID 0000-0002-4352-1370 Emma H KelleyDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.ORCID 0000-0002-3638-7628 Teerana ThabthimthongDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.
Alayna BlandDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.
Katherine KonczakDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.
Katherine J TormaDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.
Thahani S Habeeb MohammadDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.
Kenneth W OlsenDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.
Daniel P BeckerDepartment of Chemistry and Biochemistry, Loyola University Chicago, 1032 West Sheridan Road, Chicago, IL 60660, USA.ORCID 0000-0001-9392-0460 Funding
Loyola University Carbon Fellows Program Carbon Fellowship for Katherine KonczakLoyola University Chicago Office of Research Services (ORS) Internal Research Award (IRA) IPRS# 1083.
6 · The paper itselfAbstract
Based on the inhibitory potencies from earlier reported tetrazole thioether analogs, we now describe the synthesis and inhibition of pyrazole-based inhibitors of
Indexed as
AmidohydrolasesAnti-Bacterial AgentsEnzyme InhibitorsHaemophilus influenzaePyrazolesCatalytic DomainKineticsMolecular Docking SimulationStructure-Activity RelationshipAmidohydrolasesAnti-Bacterial AgentsEnzyme InhibitorsN-succinyl-l,l-diaminopimelic acid desuccinylasepyrazolePyrazolesantibioticDapEmetalloenzymeninhydrin
Identifiers
PMID39795881
PMCPMC11720106
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