Changes in the Phenotype and Metabolism of Peritoneal Macrophages in Mucin-2 Knockout Mice and Partial Restoration of Their Functions In Vitro After L-Fucose Treatment.

Elena L Arzhanova, Yulia Makusheva, Elena G Pershina, Snezhanna S Medvedeva, Ekaterina A Litvinova

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elena L ArzhanovaFaculty of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.ORCID 0009-0006-1066-1867

Yulia MakushevaPhysical Engineering Faculty, Novosibirsk State Technical University, 630073 Novosibirsk, Russia.

Elena G PershinaFaculty of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.ORCID 0000-0003-2658-7906

Snezhanna S MedvedevaInstitute of Molecular and Cellular Biology, 630090 Novosibirsk, Russia.ORCID 0000-0002-3158-5350

Ekaterina A LitvinovaPhysical Engineering Faculty, Novosibirsk State Technical University, 630073 Novosibirsk, Russia.ORCID 0000-0001-6398-7154

Funding

Institute of Cytology and Genetics SB RAS, budget project FWNR: 2022-0015

6 · The paper itself

Abstract

In the development of inflammatory bowel disease (IBD), peritoneal macrophages contribute to the resident intestinal macrophage pool. Previous studies have demonstrated that oral administration of L-fucose exerts an immunomodulatory effect and repolarizes the peritoneal macrophages in vivo in mice. In this study, we analyzed the phenotype and metabolic profile of the peritoneal macrophages from

Indexed as

FucoseMacrophages, PeritonealMucin-2Adenosine TriphosphateAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutMitochondriaPhenotypeAdenosine TriphosphateFucoseMuc2 protein, mouseMucin-2fucoseinflammatory bowel diseasemacrophagesmucin-2

Identifiers

PMID39795876

DOI10.3390/ijms26010013

PMCPMC11719744

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.