Evidence map›Paper›PMID 39795524›Full record

ArticlePolymers2025

Artificial Intelligence-Driven Modeling for Hydrogel Three-Dimensional Printing: Computational and Experimental Cases of Study.

Harbil Bediaga-Bañeres, Isabel Moreno-Benítez, Sonia Arrasate, Leyre Pérez-Álvarez, Amit K Halder, M Natalia D S Cordeiro, Humberto González-Díaz, José Luis Vilas-Vilela

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Harbil Bediaga-BañeresDepartment of Physical Chemistry, University of Basque Country UPV/EHU, 48940 Leioa, Spain.ORCID 0000-0002-9055-0721
Isabel Moreno-BenítezDepartment of Organic and Inorganic Chemistry, University of Basque Country UPV/EHU, 48940 Leioa, Spain.ORCID 0000-0001-8714-9120
Sonia ArrasateDepartment of Organic and Inorganic Chemistry, University of Basque Country UPV/EHU, 48940 Leioa, Spain.
Leyre Pérez-ÁlvarezDepartment of Physical Chemistry, University of Basque Country UPV/EHU, 48940 Leioa, Spain.ORCID 0000-0003-0543-4134
Amit K HalderLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0002-4818-9047
M Natalia D S CordeiroLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0003-3375-8670
Humberto González-DíazDepartment of Organic and Inorganic Chemistry, University of Basque Country UPV/EHU, 48940 Leioa, Spain.ORCID 0000-0002-9392-2797
José Luis Vilas-VilelaDepartment of Physical Chemistry, University of Basque Country UPV/EHU, 48940 Leioa, Spain.ORCID 0000-0002-0188-4579

Funding

Basque Government Elkartek Program Grant (KK-2022/00057)Basque Government IT1756-22
6 · The paper itself

Abstract

Determining the values of various properties for new bio-inks for 3D printing is a very important task in the design of new materials. For this purpose, a large number of experimental works have been consulted, and a database with more than 1200 bioprinting tests has been created. These tests cover different combinations of conditions in terms of print pressure, temperature, and needle values, for example. These data are difficult to deal with in terms of determining combinations of conditions to optimize the tests and analyze new options. The best model demonstrated a specificity (Sp) of 88.4% and a sensitivity (Sn) of 86.2% in the training series while achieving an Sp of 85.9% and an Sn of 80.3% in the external validation series. This model utilizes operators based on perturbation theory to analyze the complexity of the data. For comparative purposes, neural networks have been used, and very similar results have been obtained. The developed tool could easily be applied to predict the properties of bioprinting assays in silico. These findings could significantly improve the efficiency and accuracy of predictive models in bioprinting without resorting to trial-and-error tests, thereby saving time and funds. Ultimately, this tool may help pave the way for advances in personalized medicine and tissue engineering.

Indexed as

artificial intelligencebioprintingdatabasehydrogelmachine learningmodeling

Identifiers

PMID39795524
PMCPMC11723248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.