ArticleMolecules (Basel, Switzerland)2025
Laser Desorption-Ion Mobility Spectrometry of Explosives for Forensic and Security Applications.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Detection and characterization of explosives and explosives residues: a review 2022-2025.Forensic science international. Synergy · 2026Review
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe detection of explosives in crime scene investigations is critical for forensic science. This study explores the application of laser desorption (LD) ion mobility spectrometry (IMS) as a novel method for this purpose utilising a new IMS prototype developed by MaSaTECH.
methodsThe LD sampling technique employs a laser diode module to vaporise explosive traces on surfaces, allowing immediate analysis by IMS without sample preparation. Chemometric approaches, including multivariate data analysis, were utilised for data processing and interpretation, including pre-processing of raw IMS plasmagrams and various pattern recognition techniques, such as linear discriminant analysis (LDA) and support vector machines (SVMs).
resultsThe IMS prototype was validated through experiments with pure explosives (TNT, RDX, PETN) and explosive products (SEMTEX 1A, C4) on different materials. The study found that the pre-processing method significantly impacts classification accuracy, with the PCA-LDA model demonstrating the best performance for real-world applications.
conclusionsThe LD-IMS prototype, coupled with effective chemometric techniques, presents a promising methodology for the detection of explosives in forensic investigations, enhancing the reliability of field applications.
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