Evidence map›Paper›PMID 39795166›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis of Novel Benzothiazole-Profen Hybrid Amides as Potential NSAID Candidates.

Iliyan Ivanov, Stanimir Manolov, Dimitar Bojilov, Yordan Stremski, Gabriel Marc, Stela Statkova-Abeghe, Smaranda Oniga, Ovidiu Oniga, Paraskev Nedialkov

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Iliyan IvanovDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Str., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-4662-3735
Stanimir ManolovDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Str., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-0314-6553
Dimitar BojilovDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Str., 4000 Plovdiv, Bulgaria.ORCID 0000-0001-6569-8348
Yordan StremskiDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Str., 4000 Plovdiv, Bulgaria.ORCID 0000-0001-8665-3130
Gabriel MarcDepartment of Organic Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400010 Cluj-Napoca, Romania.ORCID 0000-0001-9397-0388
Stela Statkova-AbegheDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Str., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-3833-6779
Smaranda OnigaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400010 Cluj-Napoca, Romania.ORCID 0000-0002-0297-7697
Ovidiu OnigaDepartment of Therapeutic Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 12 Ion Creangă Street, RO-400010 Cluj-Napoca, Romania.
Paraskev NedialkovDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Street, 1000 Sofia, Bulgaria.

Funding

National Science Fund of the Bulgarian Ministry of Education and Science КП-06-М59/5-2021Scientific Research Fund of the University of Plovdiv ФП23-ХФ-005
6 · The paper itself

Abstract

Herein, we report the synthesis of a series of new compounds by combining 2-aminobenzothiazole with various profens. The compounds were characterized using techniques such as

Indexed as

AmidesAnti-Inflammatory Agents, Non-SteroidalBenzothiazolesFree Radical ScavengersHumansHydrogen PeroxideHydroxyl RadicalLipidsMass SpectrometryMolecular Docking SimulationMolecular Dynamics SimulationProtein DenaturationSerum Albumin, HumanAmidesAnti-Inflammatory Agents, Non-SteroidalBenzothiazolesFree Radical ScavengersHydrogen PeroxideHydroxyl RadicalLipidsSerum Albumin, Humanamidesbenzothiazolehybrid moleculesin vitro biological activitylipophilicitymolecular dockingmolecular dynamicsprofens

Identifiers

PMID39795166
PMCPMC11721736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.