Evidence map›Paper›PMID 39795133›Full record

ArticleMolecules (Basel, Switzerland)2024

Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes.

Giusy Castagliuolo, Michela Di Napoli, Tshering Zangmo, Joanna Szpunar, Luisa Ronga, Anna Zanfardino, Mario Varcamonti, Diego Tesauro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Molecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giusy CastagliuoloDepartment of Biology, University of Naples "Federico II", Via Cynthia 26, 80126 Naples, Italy.
Michela Di NapoliDepartment of Biology, University of Naples "Federico II", Via Cynthia 26, 80126 Naples, Italy.
Tshering ZangmoIPREM (Institut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Matériaux), CNRS, E2S UPPA, Université de Pau et des Pays de l'Adour, CEDEX 9, 64012 Pau, France.
Joanna SzpunarIPREM (Institut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Matériaux), CNRS, E2S UPPA, Université de Pau et des Pays de l'Adour, CEDEX 9, 64012 Pau, France.ORCID 0000-0002-5644-4933
Luisa RongaIPREM (Institut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Matériaux), CNRS, E2S UPPA, Université de Pau et des Pays de l'Adour, CEDEX 9, 64012 Pau, France.
Anna ZanfardinoDepartment of Biology, University of Naples "Federico II", Via Cynthia 26, 80126 Naples, Italy.ORCID 0000-0002-6689-8365
Mario VarcamontiDepartment of Biology, University of Naples "Federico II", Via Cynthia 26, 80126 Naples, Italy.
Diego TesauroDepartment of Pharmacy and Interuniversity Research Centre on Bioactive Peptides (CIRPeB), University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-1556-2562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver drugs have played a vital role in human healthcare for the treatment of infections for many centuries. Currently, due to antibiotic resistance, a potential scenario or the application of silver complexes may arise as substitutes for conventional antibiotics. In this perspective, N-heterocyclic carbene (NHC) ligands have been selected as carrier molecules for silver ions. In this study, we selected two mono NHC-silver halide complexes: bromo[1,3-diethyl-4,5-bis(4-methoxyphenyl)imidazol-2-ylidene]silver(I) (Ag4MC) and chloro[2-pyridin- N-(2-ethylacetylamido)-2-yl-2

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsCoordination ComplexesHeterocyclic CompoundsMethaneSilverBacteriaCandida albicansEscherichia coliMicrobial Sensitivity TestsMolecular StructureAnti-Bacterial AgentsAnti-Infective AgentscarbeneCoordination ComplexesHeterocyclic CompoundsMethaneSilverantimicrobial propertiesGram (+) and Gram (−) bacteriaNHC silver complexesSEC-ICP-MS

Identifiers

PMID39795133
PMCPMC11722542

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.