Terpinen-4-ol Improves the Intestinal Barrier Function of the Colon in Immune-Stressed Weaning Piglets.

Lihuai Yu, Guangzhi Qiu, Xiaomu Yu, Jianwei Zhao, Jun Liu, Hongrong Wang, Li Dong

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

7 authors.

Lihuai YuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.

Guangzhi QiuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.ORCID 0009-0008-9801-1002

Xiaomu YuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.

Jianwei ZhaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.

Jun LiuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.

Hongrong WangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.

Li DongCollege of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the effects of terpinen-4-ol (TER) supplementation on the intestinal barrier function of pigs. Five groups of fifty 28-day-old piglets with comparable body weights were randomly assigned to the following groups: the control group (CON), the lipopolysaccharide group (LPS), the low TER group (PLT), the middle TER group (PMT), and the high TER group (PHT). The basal diet was given to the CON and LPS groups, and 30, 60, or 90 mg/kg TER was added to the basal diet for the TER groups. After the 21-day trial period, piglets in the LPS and TER groups received an intraperitoneal injection of 100 μg/kg body weight of LPS, whereas the piglets in the CON group received an injection of 0.9% normal saline solution. The results showed that LPS stimulation resulted in a decrease (

Indexed as

antioxidant functioncolonimmune functionmicrobiometerpinen-4-olweaned piglets

Identifiers

PMID39794952

DOI10.3390/ani15010009

PMCPMC11719020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.