Evidence map›Paper›PMID 39794822›Full record

ArticleBMC health services research2025

Enhancing tuberculosis case notifications through mapping sales of medicine in the private sector: a quasi-experimental study in Punjab province, Pakistan.

Beatrice Kirubi, Kinz Ul Eman, Usman R Lodhi, Razia K Fatima, Ghulam Nabi Kazi, Tahmeena Tahmeena, Syed Karam Shah, Jacob Creswell

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Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beatrice KirubiInnovations & Grants, Stop TB Partnership, Global Health Campus - Chemin du Pommier 40, Le Grand-Saconnex, 1218, Geneva, Switzerland. beatricek@stoptb.org.
Kinz Ul EmanDopasi Foundation, Islamabad, Pakistan.
Usman R LodhiDopasi Foundation, Islamabad, Pakistan.
Razia K FatimaCommon Management Unit for HIV/AIDS, TB & Malaria, Islamabad, Pakistan.
Ghulam Nabi KaziDopasi Foundation, Islamabad, Pakistan.
Tahmeena TahmeenaDopasi Foundation, Islamabad, Pakistan.
Syed Karam ShahStop TB Partnership, Islamabad, Pakistan.
Jacob CreswellInnovations & Grants, Stop TB Partnership, Global Health Campus - Chemin du Pommier 40, Le Grand-Saconnex, 1218, Geneva, Switzerland.

Funding

Global Affairs Canada CA-3-D000920001
6 · The paper itself

Abstract

introductionIn Pakistan, almost one-third of people who develop tuberculosis (TB) are missed by the National TB Program (NTP). A considerable number of people with TB receive treatment in the private sector but remain unnotified. This study documents the outcomes of an intervention to identify people with TB through private pharmacy engagement, building on mapping TB medicine sales in Punjab Province.

methodsA comprehensive intervention was carried out in four districts of Punjab with high anti-TB drug sales, comprising a policy change requiring mandatory notification of TB medication sales, mapping and engaging pharmacies selling anti-TB drugs, reporting through a novel 'eTB' mobile application and providing support via a call center. We collected both historical and prospective TB notification data from the intervention and control districts. The primary outcome was the change in TB notifications during the intervention period compared with historical and control notifications.

resultsOver the 12-month intervention period, 15,669 people with TB were reported from 2,943 pharmacies in four districts. Among the people identified, 88% were male (n = 13,673), 95% had pulmonary disease (n = 14,969), and 4,256 (27%) were bacteriologically confirmed. Chain pharmacies (n = 14) contributed to 39% of the yield. TB notifications increased by 17,462 (+ 34%) over the baseline period compared with an 8% increase in the control districts. The number of bacteriologically confirmed notifications increased by 32% compared with 16% in the control districts. The proportion of bacteriological confirmation was similar before and during the intervention.

conclusionThe results of the largest TB intervention with pharmacies globally showed incredible potential to link people with TB who are receiving care in the private sector. Mapping TB medicine sales in the private sector with tailored interventions can contribute to closing the gap in notifications where anti-TB drug sales in the private sector are prevalent.

Indexed as

Antitubercular AgentsPrivate SectorTuberculosisAdolescentAdultDisease NotificationFemaleHumansMaleMiddle AgedPakistanPharmaciesProspective StudiesYoung AdultAntitubercular AgentsCase notificationDrug quantificationMappingPakistanPrivate pharmaciesPrivate provider engagement (PPE)Private sector

Identifiers

PMID39794822
PMCPMC11720301

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