ArticleBMC medical genomics2025
Challenges of reproducible AI in biomedical data science.
Article in BMC medical genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of artificial intelligence models for temporomandibular joint anomalies on MRI: a systematic review and meta-analysis.Biomedical engineering online · 2026Pooled it
- Artificial intelligence-driven discovery of coumarin-based therapeutics: Revolutionizing target identification and validation.Pharmaceutical science advances · 2026Review
- Scalable, generalizable and uncertainty-aware integration of spatial multiomics across diverse modalities and platforms with SCIGMA.Nature genetics · 2026Article
- AI-bioinformatics synergy for precision medicine in brain diseases: integrating radiomics and multi-omics data.Briefings in bioinformatics · 2026Review
- Artificial Intelligence for Predicting Postoperative Outcomes in Anterior Segment and Ocular Adnexa Surgery: A Systematic Review.Ophthalmology science · 2026Review
- Temporal Reproducibility of Fracture Interpretation in Forensic Radiography: A Multispecialty Comparison of Physicians and Vision Language Models Including Fracture Subtype Description.Tomography (Ann Arbor, Mich.) · 2026Article
- The new frontier of newborn screening: integrating genomics, metabolomics, and data science for inborn errors of metabolism.Orphanet journal of rare diseases · 2026Review
- Statistical Competence and Editorial Policies in Biomedical Publications.Journal of Korean medical science · 2026Review
- The potential utility of in-silico approach in identifying phytochemicals against various targets for the management of lung cancer.Discover oncology · 2026Review
- AI in Drug Discovery: Clinical Failures, Regulatory Reality, and the Validation Crisis Behind the Hype.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Integrating artificial intelligence tools in health research.NPJ digital medicine · 2026Review
- AI and network biology for rational polypharmacology in signaling drug design: a review.NPJ precision oncology · 2026Review
- Comparative review of artificial intelligence for transcriptomic biomarker discovery in coronavirus disease 2019 (COVID-19).Briefings in bioinformatics · 2026Review
- The role of AI in oncology: present applications and future horizons.NPJ precision oncology · 2026Review
- Review
- Recent advancements in the application of artificial intelligence-based approaches for screening, diagnosis, prognosis and treatment of cervical cancer.Oncology reviews · 2026Review
- Recent advances in multimodal foundation model-enabled peptide screening and optimization for smart biomaterials and functional tissue engineering.Frontiers in bioengineering and biotechnology · 2026Review
- How to report neurotechnology and artificial intelligence studies in epilepsy: Peer-review-inspired recommendations.Epilepsia open · 2025Article
- Full title: evaluating AI guidelines in leading family medicine journals: a cross-sectional study.BMC primary care · 2025Article
- Beyond Binary: A Machine Learning Framework for Interpreting Organismal Behavior in Cancer Diagnostics.Biomedicines · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artificial intelligence (AI) is revolutionizing biomedical data science at an unprecedented pace, transforming various aspects of the field with remarkable speed and depth. However, a critical issue remains unclear: how reproducible are the AI models and systems employed in biomedical data science? In this study, we examine the challenges of AI reproducibility by analyzing the factors influenced by data, model, and learning complexities, as well as through a game-theoretical perspective. While adherence to reproducibility standards is essential for the long-term advancement of AI, the conflict between following these standards and aligning with researchers' personal goals remains a significant hurdle in achieving AI reproducibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.