ArticleBMC cancer2025
Impact of cancer-related fatigue on quality of life in patients with cancer: multiple mediating roles of psychological coherence and stigma.
Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of acupuncture for cancer-related fatigue: a systematic reviews and meta-analysis.Frontiers in oncology · 2026Pooled it
- Trial
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- Multinational Association of Supportive Care in Cancer (MASCC) endorsement and global perspectives on implementation of the American Society of Clinical Oncology and Society of Integrative Oncology (ASCO-SIO) fatigue in adult cancer survivors guideline.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Intolerance of uncertainty and attitudes toward cancer as predictors of spiritual well-being in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Identifying sleep disturbance- and fatigue-related factors of poor health-related quality of life in patients with advanced ovarian cancer.Journal of patient-reported outcomes · 2026Article
- Article
- Triad of agency, mood, and meaning: A nursing perspective on patient activation, depression, and quality of life in older adults receiving palliative oncology care.Palliative & supportive care · 2026Article
- Cancer-related fatigue in cancer survivors: an updated clinical practice review for healthcare providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Review
- Association between psychological resilience and global health status/quality of life in patients with brain metastases after resection of primary non-small cell lung cancer.Frontiers in psychiatry · 2026Article
- Psychosomatics at the threshold: cancer, mood disorders, and the mental pain of death - where precision medicine meets spirituality.Frontiers in psychiatry · 2026Article
- Development and validation of a machine learning model to predict moderate-to-severe cancer-related fatigue in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Assessment of Quality of Life in the Early Postoperative Period in Patients with Lung Cancer.International journal of environmental research and public health · 2025Article
- Evaluation of illness perception and treatment adherence in patients taking oral chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Mediating effects of sense of coherence and psychological resilience on stigma and quality of life among postoperative middle-aged and older patients with malignant gynecological tumors: a cross-sectional, structural equation model.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
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Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe goal of this current research was to explore the impact of cancer-related fatigue on the quality of life among patients with cancer, as well as the multiple mediating roles of psychological coherence and stigma.
methodsThis study utilized a cross-sectional design. A questionnaire was administered between November 2022 and May 2023 to 364 patients with cancer in two tertiary hospitals in Jinzhou City, Liaoning Province, China. The questionnaires included the General Information Questionnaire, Cancer-Related Fatigue Questionnaire, Psychological Coherence Scale, Stigma Scale, and Quality of Life Questionnaire. SPSS 25.0 and PROCESS 3.5 macros were used for descriptive statistics and correlation analysis of the data, as well as multiple mediation effect tests.
resultsCancer-related fatigue directly affects quality of life (β = -0.950, 95% CI = -1.138 to -0.763) and indirectly through three mediators: psychological coherence (β = -0.172, 12.58% of total effect), stigma (β = -0.193, 14.12% of total effect), and both psychological coherence and stigma (β = -0.052, 3.80% of total effect), totaling a 30.50% mediating effect.
conclusionOverall, psychological coherence and stigma may play an important mediating role between cancer-related fatigue and quality of life in patients with cancer. This suggests that alleviating cancer-related fatigue, while enhancing psychological coherence and reducing stigma, could be effective strategies for improving patients' quality of life. Therefore, healthcare professionals and related professionals should pay attention to and adopt effective interventions to alleviate cancer-related fatigue, enhance psychological coherence, and reduce stigma, thereby contributing to the overall well-being and quality of life of patients with cancer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.