Evidence map›Paper›PMID 39794712›Full record

ReviewBMC surgery2025

Microvascular decompression: a contemporary update.

Inibehe Ime Okon, Sidharth Sunil Menon, Mahmoud Osama, Maidan Aiman, Luis F Fabrini Paleare, Don Lucero-Prisno Eliseo, Muhammad Danish Shafqat, Chizowa Okwuchukwu Ezeaku, Márcio Yuri Ferreira, Youssef Razouqi and 11 more

Registry-linked trialAbstract readReview
In one paragraph

Review in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07046247 (Effect of Teflon Implant on Nerve Tissue and Its Relationship With Recurrences in the Treatment of Trigeminal Neuralgia by Microvascular Decompression, With Special Attention to the Method of Application), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07046247 completednot on this map

Effect of Teflon Implant on Nerve Tissue and Its Relationship With Recurrences in the Treatment of Trigeminal Neuralgia by Microvascular Decompression, With Special Attention to the Method of Application: A Retrospective Clinical Study

TypeobservationalSponsorUniversity of ValenciaRan2025 to 2025Enrolled150ConditionsTrigeminal Neuralgia, Microvascular Decompression, TeflonArmsMicrovascular decompression for trigeminal neuralgia
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Surgical treatment of otogenic vertigo.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Inibehe Ime OkonDepartment of Research, Medical Research Circle (MedReC), Bukavu, DR, Congo. inibeheokon3@gmail.com.ORCID http://orcid.org/0009-0003-8275-5713
Sidharth Sunil MenonUniversity College London Medical School, 74 Huntley St, Bloomsbury, London, WC1E 6DE, UK.
Mahmoud OsamaDepartment of Neurosurgery, Yeditepe University, Istanbul, Turkey.
Maidan AimanDepartment of Vascular Neurosurgery, National Centre for Neurosurgery, Astana, Kazakhstan.
Luis F Fabrini PalearePontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Don Lucero-Prisno EliseoDepartment of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Muhammad Danish ShafqatDepartment of Internal Medicine, Shifa International Hospital, Islamabad, Pakistan.
Chizowa Okwuchukwu EzeakuDepartment of Neurosurgery, Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife Osun State, Ife, Nigeria.
Márcio Yuri FerreiraDepartment of Neurosurgery, Lenox Hill Hospital/Northwell Health, New York, NY, USA.
Youssef RazouqiMohammed VI Higher Institute of Biosciences and Biotechnologies, Mohammed VI University of Sciences and Health, Casablanca, Morocco.
Marianna KapsetakiDepartment of Neurosurgery, St. George's University Hospital, London, UK.
Jovy Dia Remolino SanielSchool of Nursing and Health Sciences, Biliran Province State University, Naval, Biliran, Philippines.
Naneta M PanitSchool of Teacher Education, Biliran Province State University, Naval, Biliran, Philippines.
Asad Gul RaoDow Medical College, Karachi, Pakistan.
Umer IqbalShaheed Mohtarma Benazir Bhutto Medical College, Lyari Hospital Rd, Rangiwara Karachi, Karachi, 75010, Pakistan.
Daniel David OtoboGlobal Surgery Fellow, Operation Smile Inc. VA, Virginia Beach, USA.
Ibraheem M AlkhawaldehFaculty of Medicine, Mutah University, Al-Karak, Jordan.
Felipe Salvagni PereiraMackenzie Evangelical College of Paraná, Curitiba, Brazil.
Imad AkbarDepartment of Surgery, Ayub Medical College, Abbottabad, Pakistan.
Omar KasimiehCollege of Medicine, University of the East Ramon Magsaysay Memorial Medical Center, Manilla, Philippines.
Bipin ChaurasiaDepartment of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrovascular decompression (MVD) is the gold-standard surgical treatment for cranial nerve compression disorders, including trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia (GPN). This review synthesizes historical milestones, recent advances, and evolving techniques in MVD, with a primary focus on these conditions.

methodsA comprehensive literature review was conducted using databases such as PubMed, SpringerLink, Google Scholar, BioMed Central, Scopus, and ScienceDirect. Studies published between 1970 and 2024 were analyzed, emphasizing surgical techniques, clinical outcomes, and technological innovations in MVD. Articles addressing TN, HFS, GPN, and other cranial nerve disorders treated with MVD were selected for detailed evaluation.

resultsMVD demonstrates high efficacy, with 80-90% of patients achieving immediate symptom relief. Nevertheless, 15-25% of patients experience symptom recurrence, though long-term outcomes remain favorable. Fully endoscopic MVD has shown potential for enhanced intraoperative visualization, particularly in complex anatomical regions; however, its impact on surgical precision and clinical outcomes is still under investigation. Moreover, innovations in visualization technologies, including three-dimensional exoscopic systems and artificial intelligence-assisted surgery, continue to improve procedural safety and outcomes. Despite these advancements, complications such as hearing loss (1-2%) and cerebrospinal fluid leakage (2-4%) persist, highlighting the need for continuous refinement of techniques.

conclusionsMVD is evolving with the integration of cutting-edge technologies, resulting in improved clinical outcomes and reduced complication rates. Emerging innovations such as robotic-assisted MVD and gene therapies for cranial nerve disorders, including TN and GPN, promise even greater efficacy and precision. However, further research is necessary to standardize surgical protocols and address disparities in healthcare systems globally.

Indexed as

Microvascular Decompression SurgeryHemifacial SpasmHumansTreatment OutcomeTrigeminal NeuralgiaContemporary updateGlossopharyngeal neuralgiaHemifacial spasmMicrovascular decompressionTrigeminal neuralgia

Identifiers

PMID39794712
PMCPMC11724535

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.