Evidence map›Paper›PMID 39794685›Full record

ArticleBMC genomics2025

Genetic parameters and genome-wide association studies including the X chromosome for various reproduction and semen quality traits in Nellore cattle.

Felipe E de Carvalho, José Bento S Ferraz, Victor B Pedrosa, Elisangela C Matos, Joanir P Eler, Marcio R Silva, José D Guimarães, Fernando Bussiman, Barbara C A Silva, Henrique A Mulim and 5 more

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Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Felipe E de CarvalhoDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil. felipe.eguti@usp.br.
José Bento S FerrazDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil.
Victor B PedrosaDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA.
Elisangela C MatosDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil.
Joanir P ElerDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil.
Marcio R SilvaDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil.
José D GuimarãesDepartment of Veterinary Medicine, Federal University of Vicosa, Vicosa, MG, Brazil.
Fernando BussimanDepartment of Animal and Dairy Science, University of Georgia, Athens, GA, USA.
Barbara C A SilvaDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga, SP, Brazil.
Henrique A MulimDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA.
Artur Oliveira RochaDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA.
Andre C AraujoDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA.
Hui WenDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA.
Gabriel S CamposDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA.
Luiz F BritoDepartment of Animal Sciences, Purdue University, 270 S. Russell Street, West Lafayette, IN, 47907, USA. britol@purdue.edu.

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/14641-4
6 · The paper itself

Abstract

backgroundThe profitability of the beef industry is directly influenced by the fertility rate and reproductive performance of both males and females, which can be improved through selective breeding. When performing genomic analyses, genetic markers located on the X chromosome have been commonly ignored despite the X chromosome being one of the largest chromosomes in the cattle genome. Therefore, the primary objectives of this study were to: (1) estimate variance components and genetic parameters for eighteen male and five female fertility and reproductive traits in Nellore cattle including X chromosome markers in the analyses; and (2) perform genome-wide association studies and functional genomic analyses to better understand the genetic background of male and female fertility and reproductive performance traits in Nellore cattle.

resultsThe percentage of the total direct heritability (h

conclusionsOur findings indicate the key role of genes located on the X chromosome on the phenotypic variability of male and female reproduction and fertility traits in Nellore cattle. Breeding programs aiming to improve these traits should consider adding the information from X chromosome markers in their genomic analyses.

Indexed as

ReproductionSemenX ChromosomeAnimalsCattleFemaleGene Expression RegulationGenomeGenome-Wide Association StudyMaleGWASHeritabilityReproductive performanceZebu cattle

Identifiers

PMID39794685
PMCPMC11720523

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.