ArticleAJNR. American journal of neuroradiology2025
Frontal Paraventricular Cysts: Refined Definitions and Outcomes.
Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Paediatric cranial ultrasound: assessment of the preterm brain.Insights into imaging · 2025Article
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6 authors.
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Abstract
background and purposeFrontal paraventricular cystic changes have a varied etiology that includes connatal cysts, subependymal pseudocysts, necrosis, and enlarged perivascular spaces. These may be difficult to distinguish by neuroimaging and have a variety of associated prognoses. We aim to refine the neuroimaging definition of frontal horn cysts and correlate it with adverse clinical conditions. MATERIALS AND
methodsIn this cross-sectional study, the pre- and postnatal neuroimaging database at a quaternary referral children's hospital was searched for all reports containing "frontal horn cysts," "periventricular cysts," or "connatal cysts" after internal review board exemption. Frontal paraventricular abnormalities were categorized as either cysts, necroses, enlarged perivascular spaces, caudothalamic groove subependymal pseudocysts, frontal horn asymmetries, intraventricular septations, or ependymal vessels based on location and appearance. Cyst number, size, location, morphology, and signal/attenuation/echotexture were documented, as were additional brain abnormalities. Clinical outcomes were recorded when available. Fisher exact and χ
resultsTwo hundred five brain imaging examinations (148 MRI; 55 ultrasound [US]; 2 CT) from 110 distinct subjects (5 fetal: median 29.3, mean 27.5, and range 22.4 to 32.8 gestational weeks; 105 postnatal: mean 2.5 years, median 15 days, range 0 days to 19 years) were included. Seventy-one examinations (35%) were initially diagnosed as connatal cysts but, instead, represented necrosis (
conclusionsFrontal paraventricular cystic changes represent a common interpretive dilemma. Enlarged perivascular spaces should be distinguished from other frontal cystic changes, which portend a more guarded prognosis, whether necrotic or otherwise.
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