Evidence map›Paper›PMID 39793548›Full record

ReviewJCO oncology practice2025

Social and Legal Needs in Patients and Families With Cancer: Interaction With Patient-Level Financial Toxicity.

Shruti Anant, Changchuan Jiang, Joanna Doran, Francesca Gany, Arjun Gupta, Gabrielle B Rocque, Louise K Knight, S M Qasim Hussaini

Abstract readReview
In one paragraph

Review in JCO oncology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Sociodemographic Factors related to Financial Toxicity among Cancer Patients and Survivors:"The Second Cancer Patient Experience Survey" - A Nationwide Study in Japan.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Patient-, care partner-, and clinician-proposed solutions to address the time toxicity of cancer care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shruti AnantJohns Hopkins School of Medicine, Baltimore, MD.
Changchuan JiangDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.ORCID 0000-0002-7392-4154
Joanna DoranTriage Cancer, Chicago, IL.ORCID 0009-0004-5666-7952
Francesca GanyImmigrant Health and Cancer Disparities Service, Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0003-0684-2367
Arjun GuptaMasonic Cancer Center, University of Minnesota, Minneapolis, MN.ORCID 0000-0003-0875-4731
Gabrielle B RocqueO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0003-4188-9785
Louise K KnightJohns Hopkins School of Medicine, Baltimore, MD.
S M Qasim HussainiJohns Hopkins School of Medicine, Baltimore, MD.ORCID 0000-0002-8006-5343

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Research Project 1U54CA280770 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MONA N. FOUAD, MARIA PISU · 2023 to 2026
$9.6M
NCI NIH HHS P30 CA008748NCI NIH HHS U54 CA280770
6 · The paper itself

Abstract

Adverse financial burden and its effect on patients resulting from the costs associated with cancer care, both direct and indirect, is known as financial toxicity. This review explores the interplay between financial toxicity and key social and legal needs in cancer care. Drawing from the WHO's framework and the ASCO's policy statement on social determinants of health, we propose a conceptual model that discusses five key needs-housing insecurity, food insecurity, transportation and access barriers, employment disruptions, and psychosocial needs-which interact with, and are affected by financial toxicity, and adversely influence patients' well-being and adherence to treatment. We review literature addressing the scope of each of these key needs, their effect on patients with cancer, and how each increases the overall burden of cancer treatment. There is an emphasis on both the patient and the caregiver as one unit navigating through cancer treatment together. The aim is to guide interventions at the patient-provider, institutional, and policy levels that alleviate financial toxicity and improve overall care delivery for patients and caregivers by addressing underappreciated social and legal needs.

Indexed as

Cost of IllnessNeoplasmsCaregiversHumans

Identifiers

PMID39793548
PMCPMC11733742

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.