Evidence map›Paper›PMID 39793084›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Synapse-specific catecholaminergic modulation of neuronal glutamate release.

Dariya Bakshinska, William YuChen Liu, Ryan Schultz, R Steven Stowers, Adam Hoagland, Caroline Cypranowska, Cherise Stanley, Susan H Younger, Zachary L Newman, Ehud Y Isacoff

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Octopamine receptors inFrontiers in molecular neuroscience · 2026
    Article
  6. Octopamine instructs head direction plasticity.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Monoamine-induced diacylglycerol signaling rapidly accumulates Unc13 in nanoclusters for fast presynaptic potentiation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Deficiency in transmitter release triggers homeostatic transcriptional changes that increase presynaptic excitability.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dariya BakshinskaHelen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720.
William YuChen LiuDepartment of Neuroscience and Molecular & Cell Biology, University of California, Berkeley, CA 94720.
Ryan SchultzHelen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720.
R Steven StowersDepartment of Microbiology & Cell Biology, Montana State University, Bozeman, MT 59717.ORCID 0000-0002-1473-2478
Adam HoaglandDepartment of Neuroscience and Molecular & Cell Biology, University of California, Berkeley, CA 94720.
Caroline CypranowskaDepartment of Neuroscience and Molecular & Cell Biology, University of California, Berkeley, CA 94720.
Cherise StanleyDepartment of Neuroscience and Molecular & Cell Biology, University of California, Berkeley, CA 94720.
Susan H YoungerDepartment of Neuroscience and Molecular & Cell Biology, University of California, Berkeley, CA 94720.
Zachary L NewmanDepartment of Neuroscience and Molecular & Cell Biology, University of California, Berkeley, CA 94720.
Ehud Y IsacoffHelen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720.ORCID 0000-0003-4775-9359

Funding

Neuroscience Training Program at UC BerkeleyT32NS095939 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BATEUP, HELEN S. · 2016 to 2025
$6.3M
Functional role of dual neurotransmitter usage in aggressionR01GM115510 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Sarah J Certel, Karla R. Kaun · 2015 to 2026
$3.1M
Synaptic to circuit homeostasis in the Drosophila locomotor systemR01NS107506 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ISACOFF, EHUD · 2019 to 2023
$1.6M
Upgrade for time-correlated single photon counting fluorescence lifetime laser scanning confocal microscopeS10OD025063 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI AARON, HOLLY L · 2019 to 2019
$862k
Molecular determinants of synaptic diversity at the nanoscaleF31NS122421 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BAKSHINSKAYA, DARIYA · 2022 to 2023
$84k
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R01GM115510HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS107506NIGMS NIH HHS R01 GM115510NIH HHS S10 OD025063NINDS NIH HHS F31 NS122421NINDS NIH HHS R01 NS107506NINDS NIH HHS T32 NS095939
6 · The paper itself

Abstract

Norepinephrine in vertebrates and its invertebrate analog, octopamine, regulate the activity of neural circuits. We find that, when hungry,

Indexed as

Glutamic AcidMotor NeuronsOctopamineReceptors, Biogenic AmineSynapsesAnimalsDrosophilaDrosophila melanogasterDrosophila ProteinsLarvaLocomotionSynaptic TransmissionDrosophila ProteinsGlutamic Acidnorsynephrine receptorOctopamineReceptors, Biogenic AmineglutamateoctopamineQuaSORsynapseUnc13

Identifiers

PMID39793084
PMCPMC11725921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.