Evidence map›Paper›PMID 39793062›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Integrin-activating

Joost J A P M Wijnakker, Gijs J F van Son, Daniel Krueger, Willine J van de Wetering, Carmen Lopez-Iglesias, Robin Schreurs, Fenna van Rijt, Sangho Lim, Lin Lin, Peter J Peters and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Animal-Free Intestinal Epithelial 2D "Organoid-Sheet" Cultures Using Invasin.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Anti-infective compounds forSustainable microbiology · 2026
    Review
  13. Biomaterials in organoid research: current state and future directions.Frontiers in bioengineering and biotechnology · 2026
    Review
  14. Invasin-functionalized PIC hydrogels enable long-term 3D culture of epithelial organoids.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Integrin-activatingProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Joost J A P M WijnakkerOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.
Gijs J F van SonPrincess Maxima Center of Pediatric Oncology, Utrecht 3584 CS, The Netherlands.
Daniel KruegerOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.
Willine J van de WeteringThe Maastricht Multimodal Imaging Institute, Maastricht University, Maastricht 6229 ER, The Netherlands.ORCID 0000-0003-0311-978X
Carmen Lopez-IglesiasThe Maastricht Multimodal Imaging Institute, Maastricht University, Maastricht 6229 ER, The Netherlands.
Robin SchreursOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.
Fenna van RijtPrincess Maxima Center of Pediatric Oncology, Utrecht 3584 CS, The Netherlands.
Sangho LimOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.
Lin LinOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.
Peter J PetersThe Maastricht Multimodal Imaging Institute, Maastricht University, Maastricht 6229 ER, The Netherlands.
Ralph R IsbergDepartment of Molecular Biology and Microbiology, School of Medicine, Tufts University, Boston, MA 02111.
Claudia Y JandaPrincess Maxima Center of Pediatric Oncology, Utrecht 3584 CS, The Netherlands.
Wim de LauOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.
Hans CleversOncode Institute, Hubrecht Institute-Royal Netherlands Academy of Arts and Science, Utrecht 3584 CT, The Netherlands.ORCID 0000-0002-3077-5582

Funding

Material Driven Regeneration 024.003.013 ZWK MDROncode Institute NGFOP2201
6 · The paper itself

Abstract

Matrigel

Indexed as

Adhesins, BacterialEpithelial CellsLamininOrganoidsAnimalsCell AdhesionCollagenDrug CombinationsHumansIntegrin alpha6beta1MiceProteoglycansAdhesins, BacterialCollagenDrug CombinationsIntegrin alpha6beta1invasin, YersiniaLamininmatrigelProteoglycansintegrinInvasinmatrigelorganoidstem cells

Identifiers

PMID39793062
PMCPMC11725944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.