Evidence map›Paper›PMID 39793028›Full record

ArticleJournal of the American Chemical Society2025

Advancing the Mechanosensitivity of Atropisomeric Diarylethene Mechanophores through a Lever-Arm Effect.

Cijun Zhang, Tatiana B Kouznetsova, Boyu Zhu, Liam Sweeney, Max Lancer, Ivan Gitsov, Stephen L Craig, Xiaoran Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cijun ZhangDepartment of Chemistry, BioInspired Institute, Syracuse University, Syracuse, New York 13244, United States.
Tatiana B KouznetsovaDepartment of Chemistry, Duke University, Durham, North Carolina 27708, United States.
Boyu ZhuDepartment of Chemistry, BioInspired Institute, Syracuse University, Syracuse, New York 13244, United States.
Liam SweeneyDepartment of Chemistry, BioInspired Institute, Syracuse University, Syracuse, New York 13244, United States.
Max LancerDepartment of Chemistry, BioInspired Institute, Syracuse University, Syracuse, New York 13244, United States.ORCID 0009-0009-5104-5886
Ivan GitsovDepartment of Chemistry, The Michael M. Szwarc Polymer Research Institute, State University of New York - ESF, Syracuse, New York 13210, United States.ORCID 0000-0001-7433-8571
Stephen L CraigDepartment of Chemistry, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0002-8810-0369
Xiaoran HuDepartment of Chemistry, BioInspired Institute, Syracuse University, Syracuse, New York 13244, United States.ORCID 0000-0001-7598-4516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding structure-mechanical activity relationships (SMARs) in polymer mechanochemistry is essential for the rational design of mechanophores with desired properties, yet SMARs in noncovalent mechanical transformations remain relatively underexplored. In this study, we designed a subset of diarylethene mechanophores based on a lever-arm hypothesis and systematically investigated their mechanical activity toward a noncovalent-yet-chemical conversion of atropisomer stereochemistry. Results from Density functional theory (DFT) calculations, single-molecule force spectroscopy (SMFS) measurements, and ultrasonication experiments collectively support the lever-arm hypothesis and confirm the exceptional sensitivity of chemo-mechanical coupling in these atropisomers. Notably, the transition force for the diarylethene

Identifiers

PMID39793028
PMCPMC11760174

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.