SynthesisEuropean child & adolescent psychiatry2025
Transcranial direct current stimulation (tDCS) in psychiatric disorders in early childhood (aged under 10 years): a systematic review.
Synthesis in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Integrated Interventions for Executive Function Deficits in Children with Autism Spectrum Disorder: From Cognitive Training to Neuroregulation.Alpha psychiatry · 2026Review
- Neuronal network analysis during short time transcranial direct current stimulation with permanent EEG measurement in early childhood: a feasibility study.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial direct current stimulation (tDCS) remains experimental for many psychiatric disorders in adults. Particularly in childhood, there is limited research on the evidence for the efficacy and mechanisms of action of tDCS on the developing brain. The objective of this review is to identify published experimental studies to examine the efficacy and mechanisms of tDCS in children with psychiatric or developmental disorders in early (prepubertal) childhood (aged under 10 years). Included Studies should meet the following criteria: (1) experimental studies (no reviews, no case reports), (2) studies published in international peer-reviewed journals, (3) written in English, (4) conducted on children under 10 under years of age, (5) at enrolment with a psychiatric or developmental disorder.Eight studies were identified that fulfilled the specified criteria. All studies investigated effect on children with autism-spectrum-disorder (ASD). Anodal tDCS, mainly targeting the left dorsolateral prefrontal cortex (dlPFC), showed positive effects on the reduction of ASD symptoms. There has also been evidence that these stimulations are feasible, have good tolerability and are safe. tDCS was found to be safe and partially effective, but a long-term effect of tDCS and changes in connectivity during tDCS in autism has not been proven. Other developmental or psychiatric diseases were not investigated. This results in a lack of knowledge regarding the reactivity of the brain during the prepubertal period, which is a critical phase in the pathogenesis of neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD), ASD, Tourette's syndrome or dyslexia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.