Evidence map›Paper›PMID 39792249›Full record

ArticlePediatric cardiology2026

Extracorporeal Membrane Oxygenation in Children with Pulmonary Atresia and Intact Ventricular Septum: Mortality and Associated Outcomes.

Saul Flores, Rohit S Loomba, Christopher W Mastropietro, Eva Cheung, Venugopal Amula, Monique R Radman, David M Kwiatkowski, Bao N Puente, Jason R Buckley, Kiona Y Allen and 12 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Saul FloresDepartment of Pediatrics, Division of Critical Care and Cardiology, Baylor College of Medicine, Texas Children's Hospital, 6651 Main Street, 14th Floor, Houston, TX, 77030, USA. saul.flores2@bcm.edu.
Rohit S LoombaDivision of Cardiology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Christopher W MastropietroDivision of Critical Care, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USA.
Eva CheungDepartment of Pediatrics, Columbia University College of Physicians & Surgeons, Morgan Stanley Children's Hospital of New York, New York, NY, USA.
Venugopal AmulaDivision of Critical Care, Department of Pediatrics, University of Utah School of Medicine, Intermountain Primary Children's Hospital, Salt Lake City, UT, USA.
Monique R RadmanDivision of Critical Care, Department of Pediatrics, University of Washington, Seattle Children's Hospital, Seattle, WA, USA.
David M KwiatkowskiDivision of Cardiology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, CA, USA.
Bao N PuenteDivision of Cardiac Critical Care, Children's National Health System, Washington, DC, USA.
Jason R BuckleyDivision of Cardiology, Department of Pediatrics, Shawn Jenkins Children's Hospital, Medical University of South Carolina, Charleston, SC, USA.
Kiona Y AllenDivision of Cardiology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Karan B KarkiDivision of Cardiology, Department of Pediatrics, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, TN, USA.
Saurabh ChiwaneDivision of Critical Care Medicine, Department of Pediatrics, Loma Linda Children's Hospital, Loma Linda University, California, USA.
Katherine CashenDepartment of Pediatrics, Division of Critical Care Medicine, Duke University and Duke University Health System, Durham, NC, USA.
Kurt PiggottDivision of Critical Care, LSU Health Sciences, Children's Hospital, New Orleans, LA, USA.
Yamini KapileshwarkarDepartment of Pediatrics, Children's Hospital of Illinois, Peoria, IL, USA.
Keshava M N GowdaDepartment of Pediatrics, Cleveland Clinic, Cleveland, OH, USA.
Aditya BadhekaDepartment of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.
Rahul RamanDepartment of Pediatrics, Mercy Medical Center, Des Moines, IA, USA.
Huaiyu ZangThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
John M CostelloDivision of Cardiology, Department of Pediatrics, Shawn Jenkins Children's Hospital, Medical University of South Carolina, Charleston, SC, USA.
Ilias IliopoulosDepartment of Pediatrics, Inova Children's Hospital, Fairfax, VA, USA.
Collaborative Research From the Pediatric Cardiac Intensive Care Society Investigators.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on outcomes of extracorporeal membrane oxygenation (ECMO) are limited in patients with pulmonary atresia intact ventricular septum (PAIVS). The objective of this study was to describe the use of ECMO and the associated outcomes in patients with PAIVS. We retrospectively reviewed neonates with PAIVS who received ECMO between 2009 and 2019 in 19 US hospitals affiliated with the Collaborative Research for the Pediatric Cardiac Intensive Care Society (CoRe-PCICS). Patients who received ECMO were compared to those who did not and patients on ECMO who died were compared to those who survived by bivariate analysis and multivariable logistic regression. The predictive ability of a risk score for inpatient mortality (using beta coefficients) was assessed by receiver operator curve analysis. Of 295 identified patients, 32 (11%) were supported with extracorporeal membrane oxygenation. Of these, 15 (46%) experienced mortality. A higher left pulmonary artery z-score (beta coefficient 0.72) and the presence of ventriculocoronary connections by cardiac catheterization (beta coefficient 1.25) were associated with an increased risk of ECMO (p-value < 0.01). The resulting risk score had an area under the curve of 0.71 (p-value 0.03) for the prediction of need for ECMO. In a multicenter cohort of patients with PAIVS, 11% received ECMO. Of those supported with ECMO, 46% experienced inpatient mortality. A higher left pulmonary artery z-score and the presence of ventriculocoronary connections appear to be risk factors for the use of ECMO.

Indexed as

Extracorporeal Membrane OxygenationHeart Defects, CongenitalPulmonary AtresiaFemaleHospital MortalityHumansInfantInfant, NewbornMaleRetrospective StudiesRisk FactorsUnited StatesCongenital Heart DiseaseCongenital Heart SurgeryPulmonary Atresia Intact Ventricular SeptumRight Ventricular Dependent Coronary Circulation

Identifiers

PMID39792249

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.