Evidence map›Paper›PMID 39792164›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Current status and trend of global research on the pharmacological effects of emodin family: bibliometric study and visual analysis.

Miao Luo, Luorui Shang, Jiao Xie, Tao Zhou, Chengyi He, David Fisher, Khrystyna Pronyuk, Erkin Musabaev, Nguyen Thi Thu Hien, Huan Wang and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miao Luo *Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Luorui Shang *Department of Clinical Nutrition, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jiao Xie *Health Management Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Tao ZhouDepartment of Gastroenterology and Hepatology, Huanggang Hospital of Traditional Chinese Medicine, Huanggang, Hubei, China.
Chengyi HeDepartment of Vascular Surgery, the Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
David FisherDepartment of Medical Biosciences, Faculty of Natural Sciences, University of The Western Cape, Cape Town, South Africa.
Khrystyna PronyukInfectious Diseases Department, O.Bogomolets National Medical University, Kiev, Ukraine.
Erkin MusabaevThe Research Institute of Virology, Ministry of Health, Tashkent, Uzbekistan.
Nguyen Thi Thu HienHai Phong University of Medicine and Pharmacy, Hai Phong, Vietnam.
Huan WangDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. huanwang2009@163.com.
Lei ZhaoDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. leizhao@hust.edu.cn.

Funding

Hubei Traditional Chinese Medicine Scientific Research Project ZY2023Q026National Natural Science Foundation of China 81974530
6 · The paper itself

Abstract

Emodin, as a natural active ingredient, has shown great application potential in the fields of medicine, food and cosmetics due to its unique pharmacological effects, such as anti-inflammatory, antioxidant, anti-cancer, etc. In recent years, with the development of science and technology and the increase of people's demand for natural medicine, emodin research has been paid more and more attention by the global scientific research community. The bibliometric analysis of emodin and the construction of knowledge map are still blank. We searched the publications of emodin related studies in the Web of Science Core Collection (WoSCC) database from 2004 to 2024 and conducted a bibliometric analysis. Data processing was done using the R packages Bibliometrix, VOSviewer and CiteSpace. The consensus identified 4,125 emodin related articles from multiple countries, with China being the main contributor. The number of publications in this field is increasing year by year. China Medical University, the Chinese Academy of Sciences, and Nanjing University of Traditional Chinese Medicine are all prominent research institutions in this field. The Journal of ethnopharmacology published the most articles on the subject. The total number of authors of these articles has reached 14,991, among which Yi Wang is the author with the most output and Xiaoxv Dong is the author with the most cited times. "emodin", "apoptosis", and "liver injury" were the main research focuses. Topics such as "pharmacology", "photodynamic therapy", "advancing drug discovery" and "gallbladder cancer cell" may represent emerging areas of research in medicine. The results of this study help to identify the latest research frontiers and hot topics, and provide a valuable reference for the study of emodin family.

Indexed as

BibliometricsBiomedical ResearchEmodinAnimalsHumansEmodinBibliometricCitespaceEmodinLiver injuryVOSviewer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.