Evidence map›Paper›PMID 39791878›Full record

ArticleApplied and environmental microbiology2025

Genetic investigation of hydrogenases in

Layse C de Souza, Christopher D Herring, Lee R Lynd

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Identification of electron transfer enzymes inJournal of bacteriology · 2025
    Article
  4. The role of AdhE mutations inJournal of bacteriology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Layse C de SouzaCentro de Engenharia Genética e Biologia Molecular (CBMEG), Universidade Estadual de Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID 0000-0003-0725-3839
Christopher D HerringTerragia Biofuel, Hanover, New Hampshire, USA.ORCID 0000-0003-1621-5906
Lee R LyndCentro de Engenharia Genética e Biologia Molecular (CBMEG), Universidade Estadual de Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID 0000-0002-5642-668X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IMPORTANCE: Our study elucidates the crucial role of electron flow and redox balancing mechanisms in improving ethanol yields from renewable biomass. We delve into the mechanism of electron transfer, highlighting the potential of key genes to be leveraged for enhanced ethanol production in anaerobic microbial species. We suggest by genetic investigation the existence of a novel Ferredoxin:NADP+ Oxidoreductase (FNOR) reaction, comprising HfsD, HydAB, and NfnAB enzymes, as a promising avenue for achieving balanced stoichiometry and efficient ethanol synthesis. Our findings not only advance the understanding of microbial metabolism but also offer practical insights for developing strategies to improve bioenergy production and sustainability.

Indexed as

Bacterial ProteinsEthanolHydrogenHydrogenaseThermoanaerobacteriumFermentationNADPOxidation-ReductionBacterial ProteinsEthanolHydrogenHydrogenaseNADPelectron flowferredoxin:NADP+oxidoreductaseferredoxin recyclinggenetic manipulationredox equilibriumT. thermosaccharolyticum

Identifiers

PMID39791878
PMCPMC11837493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.