Evidence map›Paper›PMID 39791732›Full record

ArticleCells2024

Epigenetic Inhibitors Differentially Impact TGF-β1 Signaling Cascades in COPD Airway Smooth Muscle Cells.

Karosham Diren Reddy, Dikaia Xenaki, Ian M Adcock, Brian G G Oliver, Razia Zakarya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karosham Diren ReddyRespiratory Cellular and Molecular Biology Group, Woolcock Institute of Medical Research, Macquarie University, Macquarie Park, Sydney, NSW 2113, Australia.ORCID 0000-0001-9002-6930
Dikaia XenakiRespiratory Cellular and Molecular Biology Group, Woolcock Institute of Medical Research, Macquarie University, Macquarie Park, Sydney, NSW 2113, Australia.
Ian M AdcockAirways Disease, Respiratory Cell & Molecular Biology, Airways Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London SW7 2BX, UK.ORCID 0000-0003-2101-8843
Brian G G OliverRespiratory Cellular and Molecular Biology Group, Woolcock Institute of Medical Research, Macquarie University, Macquarie Park, Sydney, NSW 2113, Australia.ORCID 0000-0002-7122-9262
Razia ZakaryaSchool of Life Science, University of Technology Sydney, Ultimo, NSW 2007, Australia.

Funding

National Health and Research Council, Australia (NHMRC) 1104704
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA MethylationEpigenesis, GeneticMyocytes, Smooth MusclePulmonary Disease, Chronic ObstructiveSignal TransductionTransforming Growth Factor beta1AcetylationFemaleHistonesHumansInterleukin-8MaleMiddle AgedNF-kappa BHistonesInterleukin-8NF-kappa BTransforming Growth Factor beta1airway smooth muscleCOPDCXCL8DNA methylationepigeneticshistone acetylationinflammationTGF-betatherapeutics

Identifiers

PMID39791732
PMCPMC11720536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.