Evidence map›Paper›PMID 39791474›Full record

ArticleMicrobiology (Reading, England)2025

The

Pauline DiGianivittorio, Lauren A Hinkel, Jacob R Mackinder, Kristin Schutz, Eric A Klein, Matthew J Wargo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology (Reading, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Sphingosine synergizes with polymyxin antibiotics againstMicrobiology (Reading, England) · 2026
    Article
  2. Article
  3. Sphingosine-mediated death ofInfection and immunity · 2025
    Article
4 · The record

Corrections and comments

  • Update of
    The2024
5 · Who and what money

Authors and funding

6 authors.

Pauline DiGianivittorioDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.
Lauren A HinkelDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.
Jacob R MackinderDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.
Kristin SchutzDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.
Eric A KleinBiology Department, Rutgers University-Camden, Camden, USA.
Matthew J WargoDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, USA.

Funding

Multidisciplinary Training in Lung BiologyT32HL076122 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI IRVIN, CHARLES G, POYNTER, MATTHEW E · 2004 to 2023
$6.1M
Vermont Immunology/Infectious Diseases Training GrantT32AI055402 · NIAID · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI GARY E WARD · 2005 to 2026
$2.7M
Pseudomonas detection and metabolism of sphingosineR01AI103003 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARGO, MATTHEW J · 2013 to 2017
$1.4M
NHLBI NIH HHS T32 HL076122NIAID NIH HHS R01 AI103003NIAID NIH HHS T32 AI055402
6 · The paper itself

Abstract

Sphingoid bases, including sphingosine, are important components of the antimicrobial barrier at epithelial surfaces where they can cause growth inhibition and killing of susceptible bacteria.

Indexed as

Bacterial ProteinsPseudomonas aeruginosaSphingosineGene DeletionOperonBacterial ProteinsSphingosinelipidpathogenesissphingosine

Identifiers

PMID39791474
PMCPMC11893366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.