Evidence map›Paper›PMID 39791129›Full record

ArticleAustralian veterinary journal2025

The efficacy of toltrazuril for prevention of oriental theileriosis (Theileria orientalis Ikeda genotype) in Friesian calves.

S G de Burgh, D L Emery

Abstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Australian veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. From Benign Parasite to Emerging Pathogen: A Review ofAnimals : an open access journal from MDPI · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S G de BurghThe University of Sydney, Sydney, New South Wales, 2006, Australia.ORCID https://orcid.org/0000-0002-4746-692X
D L EmeryThe University of Sydney, Sydney, New South Wales, 2006, Australia.

Funding

Bayer Australia Pty LtdUniversity of Sydney
6 · The paper itself

Abstract

The aim of this non-blinded, randomised, controlled study was to determine the efficacy of toltrazuril for the prevention of oriental theileriosis in calves. Thirty calves were infected with Theileria orientalis Ikeda genotype through the application and retention of infected female bush ticks (Haemaphysalis longicornis). 15 Group 1 calves were treated with a single, oral dose of toltrazuril at the dose registered in Australia for coccidiosis (15 mg/kg), concurrently with tick infection, and 15 Group 2 (control group) calves were untreated. There were no significant differences (P > 0.05) in mean parasitaemia, packed cell volume (PCV) or bodyweight between the toltrazuril treated and untreated groups at any timepoint up to Day 64 after infection, apart from a higher mean PCV for the toltrazuril treated group at Day 20. In this study, the calves treated with a single oral dose of toltrazuril (15 mg/kg) at the time of infection were not prevented from becoming infected with oriental theileriosis.

Indexed as

Cattle DiseasesCoccidiostatsTheileriaTheileriasisTriazinesAnimalsCattleFemaleGenotypeMaleCoccidiostatstoltrazurilTriazinesIkeda genotypeoriental theileriosisTheileria orientalistoltrazuriltriazine

Identifiers

PMID39791129
PMCPMC12134840

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.