Evidence map›Paper›PMID 39790994›Full record

ArticleCrohn's & colitis 3602025

Patient and Healthcare Professional Perspectives on Crohn's Perianal Fistula Treatment: Results From a Discrete Choice Experiment.

Jeanne Jiang, Bridgett Goodwin, Amod Athavale, Susan E Cazzetta, Lily Chen, Josiah Edelblut, Tao Fan, Nandini Hadker, Pradeep P Nazarey

Abstract read
In one paragraph

Article in Crohn's & colitis 360, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeanne JiangGI Medical, Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.ORCID https://orcid.org/0000-0002-7045-8928
Bridgett GoodwinGI Medical, Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.
Amod AthavaleEvidence Strategy, Trinity Life Sciences, Waltham, MA, USA.
Susan E CazzettaGI Medical, Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.
Lily ChenGI Medical, Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.
Josiah EdelblutEvidence Strategy, Trinity Life Sciences, Waltham, MA, USA.
Tao FanGI Medical, Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.
Nandini HadkerEvidence Strategy, Trinity Life Sciences, Waltham, MA, USA.
Pradeep P NazareyGI Medical, Takeda Pharmaceuticals USA, Inc., Lexington, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Crohn's perianal fistulas (CPF) are difficult to manage and often require multiple interventions. This study aimed to assess the preferences of patients and healthcare professionals (HCPs) for attributes of CPF-related procedures/surgeries to better inform CPF management. Methods: This US cross-sectional, observational study was conducted via a web-enabled questionnaire (October 2021-January 2022) among patients aged 21-89 years with a self-reported physician diagnosis of CPF (with or without CPF-related surgery experience) and HCPs (gastroenterologists and colorectal surgeons who managed ≥3 patients with CPF in the past 12 months). Patient and HCP preferences for CPF-related procedure/surgery attributes were assessed using a discrete choice experiment and stated preference methodology. Results: In total, 100 patients and 137 HCPs were recruited. Benefits of therapy (symptom control and/or fistula closure) were rated as the most important CPF treatment attribute by both patients and HCPs influencing treatment decisions (mean relative importance 23.9 and 36.3, respectively). The mean relative importance of procedure invasiveness and postoperative discomfort was higher for patients (19.3 and 20.2, respectively) than for HCPs (14.3 and 11.0, respectively), whereas the mean relative importance of fecal incontinence was greater for HCPs than patients (25.0 vs. 19.3, respectively). Conclusions: Patients and HCPs have different perspectives on the importance of specific CPF-related procedure/surgery attributes. The attributes identified as important to patients and HCPs in this study should be considered when managing patients with CPF and making treatment decisions.

Indexed as

CPF-related procedures/surgeries: Crohn’s perianal fistulasdiscrete choice experimentstated preference methodologytreatment attribute importance

Identifiers

PMID39790994
PMCPMC11711682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.