Evidence map›Paper›PMID 39790984›Full record

ArticleChemical science2025

Unveiling the enzymatic pathway of UMG-SP2 urethanase: insights into polyurethane degradation at the atomic level.

P Paiva, L M C Teixeira, R Wei, W Liu, G Weber, J P Morth, P Westh, A R Petersen, M B Johansen, A Sommerfeldt and 4 more

Abstract read
In one paragraph

Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Microbial plastic degradation: enzymes, pathways, challenges, and perspectives.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Insights into the Catalytic Activity of a Metagenome-Derived Urethanase.Journal of the American Chemical Society · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

P PaivaLAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto Rua do Campo Alegre s/n 4169-007 Porto Portugal mjramos@fc.up.pt.ORCID https://orcid.org/0000-0002-7003-6055
L M C TeixeiraLAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto Rua do Campo Alegre s/n 4169-007 Porto Portugal mjramos@fc.up.pt.ORCID https://orcid.org/0000-0002-9164-5271
R WeiJunior Research Group Plastic Biodegradation, Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, University of Greifswald Felix-Hausdorff-Str. 8 17489 Greifswald Germany.ORCID https://orcid.org/0000-0003-3876-1350
W LiuTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences 32 West Seventh Avenue, Tianjin Airport Economic Area Tianjin 300308 China.ORCID https://orcid.org/0000-0001-7954-7700
G WeberMacromolecular Crystallography, Helmholtz-Zentrum Berlin Alber-Einstein-Straße 15 12489 Berlin Germany.ORCID https://orcid.org/0000-0003-3624-1060
J P MorthEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.ORCID https://orcid.org/0000-0003-4077-0192
P WesthEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.ORCID https://orcid.org/0000-0002-6185-0637
A R PetersenEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.
M B JohansenEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.ORCID https://orcid.org/0000-0003-1638-6692
A SommerfeldtEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.ORCID https://orcid.org/0000-0003-1510-7882
A SandahlEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.
D E OtzenEnZync Center for Enzymatic Deconstruction of Thermoset Plastics.ORCID https://orcid.org/0000-0002-2918-8989
P A FernandesLAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto Rua do Campo Alegre s/n 4169-007 Porto Portugal mjramos@fc.up.pt.ORCID https://orcid.org/0000-0003-2748-4722
M J RamosLAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto Rua do Campo Alegre s/n 4169-007 Porto Portugal mjramos@fc.up.pt.ORCID https://orcid.org/0000-0002-7554-8324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recently discovered metagenomic urethanases UMG-SP1, UMG-SP2, and UMG-SP3 have emerged as promising tools to establish a bio-based recycling approach for polyurethane (PU) waste. These enzymes are capable of hydrolyzing urethane bonds in low molecular weight dicarbamates as well as in thermoplastic PU and the amide bond in polyamide employing a Ser-Ser

Identifiers

PMID39790984
PMCPMC11708778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.