Evidence map›Paper›PMID 39790945›Full record

ArticleAnnals of thoracic surgery short reports2023

Validity of Customized Branched Tissue Engineered Vascular Graft in a Porcine Model.

Hidenori Hayashi, Jacqueline Contento, Hiroshi Matsushita, Tatsuya Watanabe, Nora Lee, Tyler Dunn, Katherine Nurminsky, Angie Zhu, Emmett Reid, Paige Mass and 10 more

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Hidenori HayashiDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Jacqueline ContentoDepartment of Cardiology, Children's National Hospital, Washington, DC.
Hiroshi MatsushitaDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Tatsuya WatanabeDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Nora LeeDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Tyler DunnDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Katherine NurminskyDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Angie ZhuDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Emmett ReidDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Paige MassDepartment of Cardiology, Children's National Hospital, Washington, DC.
Vincent ClevelandDepartment of Cardiology, Children's National Hospital, Washington, DC.
Seda AslanLaboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, Maryland.
Vivian NguyenDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois.
Keigo KawajiDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois.
Joey HuddleNanofiber Solutions, LLC, Dublin, Ohio.
Jed JohnsonNanofiber Solutions, LLC, Dublin, Ohio.
Yue-Hin LokeDepartment of Cardiology, Children's National Hospital, Washington, DC.
Axel KriegerLaboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, Maryland.
Laura OlivieriDepartment of Pediatric Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Narutoshi HibinoDivision of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patient-specific, 3-dimensional printed, tissue engineered vascular grafts (3DTEVGs) are manufactured to optimize hemodynamic performance and to accommodate growth. We evaluate growth outcomes of 3DTEVGs compared with standard grafts for pulmonary artery reconstruction in porcine models. Methods: Magnetic resonance imaging (MRI) with 4-dimensional flow data was acquired in porcine models (n = 8). 3DTEVGs guided in design by computational flow dynamics were implanted (n = 4), with polytetrafluorethylene grafts used as controls (n = 4). Postoperative MRI and histologic features of explanted grafts were evaluated after 10 weeks. Results: All pigs survived, with evidence of patent grafts on postoperative MRI. Graft inner diameter changes were 0.47 ± 2.31 mm in 3DTEVGs and -4.61 ± 2.15 mm in controls ( Conclusions: Our patient-specific 3DTEVGs demonstrated optimal anatomic fit while maintaining ideal flow dynamics and promoting appropriate neovessel formation.

Identifiers

PMID39790945
PMCPMC11708597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.