Evidence map›Paper›PMID 39790938›Full record

ArticleJCEM case reports2025

Insulinoma With Ambiguous Biochemistry, Positive

Fernando Jia Jing Loo, Melvin Kok Seng Lee, Hian Liang Huang, Charles Kien Fong Vu, Yin Chian Kon

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fernando Jia Jing LooDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore 308433.ORCID https://orcid.org/0009-0004-5336-4016
Melvin Kok Seng LeeDepartment of Endocrinology, Woodlands Health Campus, Singapore 737628.
Hian Liang HuangDepartment of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore 169608.
Charles Kien Fong VuDepartment of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore 308433.
Yin Chian KonDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore 308433.ORCID https://orcid.org/0000-0002-9693-2587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 75-year-old female presented with fasting hypoglycemic episodes. A supervised fast ended at 72 hours fulfilling Whipple triad, with suppressed insulin and C-peptide levels, but discordantly suppressed serum β-hydroxybutyrate levels. After 21 months of recurring symptoms, a repeat fast ended at 48 hours with Whipple triad, suppressed serum β-hydroxybutyrate level, and borderline nonsuppressed C-peptide level, suggesting endogenous hyperinsulinism. Serum insulin levels were discordantly suppressed. Computed tomography (CT) of the abdomen demonstrated an enhancing 1.36 × 0.93-cm nodule in the head of the pancreas. Endoscopic ultrasound (EUS)-guided fine-needle aspirate of the lesion derived cytology consistent with a neuroendocrine tumor, but fine-needle core biopsy returned normal pancreatic tissue. Because the results were equivocal, functional imaging with

Indexed as

endoscopic ultrasound-guided radiofrequency ablationexendin-4 PET CTinsulinoma

Identifiers

PMID39790938
PMCPMC11711475

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.