Evidence map›Paper›PMID 39790840›Full record

ArticleEuropean journal of case reports in internal medicine2024

Kounis Syndrome Following Moxifloxacin and Deflazacort Administration.

Eugenia Morello, Silvia Bosio, Sibilla Anna Teresa Salvadeo

Abstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eugenia MorelloEmergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland.
Silvia BosioEmergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Lugano, Lugano, Switzerland.
Sibilla Anna Teresa SalvadeoEmergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Lugano, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kounis syndrome (KS), characterized by the simultaneous occurrence of acute coronary syndrome (ACS) and allergic reactions, can be triggered by a range of factors and drugs. We report on the case of a patient who arrived at our emergency department (ED) with symptoms of an allergic reaction after taking moxifloxacin and deflazacort orally. In the ED, the patient experienced a 5-minute episode of oppressive chest pain. A 12-lead electrocardiogram (ECG) was registered, and elevated troponin levels were detected in the blood, suggesting myocardial damage. The patient was admitted to the internal medicine department for observation, and a second 12-lead ECG demonstrated a significant variation in the repolarization pattern. The day after, a coronary angiography revealed no significant stenosis, thus supporting, along with elevated serum tryptase levels, the diagnosis of KS. This case report highlights two potential triggers for KS and emphasizes the critical importance of early recognition and prompt treatment of KS. LEARNING POINTS:

Indexed as

allergic reactioncoronary diseaseKounis syndrome

Identifiers

PMID39790840
PMCPMC11716304

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.