Evidence map›Paper›PMID 39790557›Full record

ArticleiScience2025

Endothelial activating transcription factor 3 promotes angiogenesis and vascular repair in the mouse retina.

Chihiro Ueda, Susumu Sakimoto, Masahito Yoshihara, Toru Takigawa, Akihiko Shiraki, Kaito Yamaguchi, Kosuke Shiki, Nobuhiko Shiraki, Shigetaka Kitajima, Yoshiaki Kubota and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chihiro UedaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Susumu SakimotoDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Masahito YoshiharaInstitute for Advanced Academic Research, Chiba University, Chiba, Japan.
Toru TakigawaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Akihiko ShirakiDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Kaito YamaguchiDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Kosuke ShikiDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Nobuhiko ShirakiDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Shigetaka KitajimaDepartment of Biochemical Genetics, Medical Research Institute and Laboratory of Genome Structure and Regulation, School of Biomedical Science, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan.
Yoshiaki KubotaDepartment of Anatomy, Keio University School of Medicine, Tokyo, Japan.
Yoko FukushimaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Kohji NishidaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemia and pathological angiogenesis in retinal vascular diseases cause serious vision-related problems. However, the transcriptional regulators of vascular repair remain unidentified. Thus, the factors and mechanisms involved in angiogenesis must be elucidated to develop approaches for restoring normal blood vessels. Here, we investigated the effects of the stress response activating transcription factor 3 (

Indexed as

OphthalmologyTranscriptomicsVascular remodeling

Identifiers

PMID39790557
PMCPMC11714383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.