Evidence map›Paper›PMID 39790537›Full record

ArticleAnnals of thoracic surgery short reports2023

Neoadjuvant Targeted Therapy in Non-Small Cell Lung Cancer and Its Impact on Surgical Outcomes.

Mark Sorin, Caroline Huynh, Merav Rokah, Laurie-Rose Dubé, Roni Rayes, Linda Ofiara, Benjamin Shieh, Scott Owen, Pierre Olivier Fiset, Sophie Cammilleri-Broët and 4 more

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mark SorinRosalind and Morris Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
Caroline HuynhRosalind and Morris Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
Merav RokahDepartment of Surgery, McGill University, Montréal, Quebec, Canada.
Laurie-Rose DubéFaculty of Medicine, McGill University, Montréal, Quebec, Canada.
Roni RayesRosalind and Morris Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
Linda OfiaraDepartment of Oncology, McGill University Health Centre, Montréal, Quebec, Canada.
Benjamin ShiehDepartment of Oncology, McGill University Health Centre, Montréal, Quebec, Canada.
Scott OwenDepartment of Oncology, McGill University Health Centre, Montréal, Quebec, Canada.
Pierre Olivier FisetDepartment of Pathology, McGill University, Montréal, Quebec, Canada.
Sophie Cammilleri-BroëtDepartment of Pathology, McGill University, Montréal, Quebec, Canada.
Sara NajmehDepartment of Surgery, McGill University, Montréal, Quebec, Canada.
Jonathan Cools-LartigueDepartment of Surgery, McGill University, Montréal, Quebec, Canada.
Lorenzo FerriDepartment of Surgery, McGill University, Montréal, Quebec, Canada.
Jonathan D SpicerRosalind and Morris Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The evidence for neoadjuvant targeted therapy in non-small cell lung cancer is limited, with 2 phase 3 trials currently recruiting and no approved indications. Methods: We describe our experience with the use of neoadjuvant targeted therapy for patients with operable non-small cell lung cancer. Results: Our focus is on surgical outcomes, which represent an underreported aspect of the patient trajectory. We argue that surgical outcomes are an essential feature of this strategy with significant potential benefits and risks. Conclusions: Overall, the patient experience can be significantly affected by the use of neoadjuvant targeted therapy and its impact on surgical planning, strategy, and outcomes.

Identifiers

PMID39790537
PMCPMC11708512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.