ArticleHeliyon2024
Complete genome characterization of foot-and-mouth disease virus My-466 belonging to the novel lineage O/ME-SA/SA-2018.
Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Molecular characterisation of foot-and-mouth disease viruses collected from Bangladesh during 2021-23: evidence for trans-pool spread of exotic viral lineages.Veterinary research · 2025Article
- Genetic characterization of foot-and-mouth disease virus in cattle in Northern Egypt.Veterinary world · 2025Article
- A comprehensive and single-use foot-and-mouth disease sero-surveillance prototype employing rationally designed multiple viral antigens.Scientific reports · 2024Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Foot-and-mouth disease virus (FMDV), the causative agent of the foot-and-mouth disease of cattle population possesses a rapid evolutionary rate. In Bangladesh, the first circulation of the O/ME-SA/SA-2018 lineage as a novel sublineage, MYMBD21 was reported from our laboratory. The first whole genome sequence of an isolate, BAN/MY/My-466/2021 (shortly named My-466) of the SA-2018 lineage is characterized and represented in this study. The genome is 8216 nucleotides long with 6996 nucleotides open reading frame flanked by 5ꞌ UTR (1-1100) and 3ꞌ UTR (8097-8216). VP1 was found to be highly variable among the structural proteins with crucial mutations in the major antigenic region, G-H loop. Structural variations of the VP1 against both field and proposed local vaccine strains were evidenced by the G-H loop displacement in a superimposed 3D model. The complete genome information of the isolate would be valuable for undertaking proper control measures needed to limit the spread of the newly emerged FMDV strain.
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