ArticleIndian journal of psychiatry2024
Evaluating prefrontal changes in depression using functional near-infrared spectroscopy utilizing Stroop test: A comparison with healthy controls.
Article in Indian journal of psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Prefrontal oxygenation during verbal fluency in severe obesity.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Utility of Functional Near-infrared Spectroscopy (fNIRS) in Major Depressive Disorder: A Systematic Review.Indian journal of psychological medicine · 2026Review
- Emotional interference and right prefrontal hemodynamic responses in adult cannabis users: a pilot fNIRS study.Frontiers in psychology · 2026Article
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8 authors.
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Abstract
Background: Functional near-infrared spectroscopy (fNIRS) is being increasingly utilized to visualize the brain areas involved in cognitive activity to understand the human brain better. Its portability and easy setup give it an advantage over other functional brain imaging tools. The current study utilizes fNIRS while performing a Stroop test, which is commonly used to assess the impairment of information selection in depression. Aim: To compare cortical activation during the Stroop test in depressed individuals to healthy controls. Methods: This cross-sectional study compared oxyhemoglobin (OxyHb) concentration changes in 39 individuals with depression to 40 healthy individuals. The Stroop test was construed in an event-related design with an intertrial interval of 2 seconds with jitter. A continuous wave fNIRS system was used for recording the cortical activity at 17 locations. Analysis of fNIRS data was done using statistical parametric mapping (SPM) for estimating general linear model (GLM) coefficients. Further analysis of the mean change of OxyHb concentrations during the 2 seconds after the presentation of congruent and incongruent stimuli was done between the groups using Mann-Whitney U test corrected for multiple comparisons with Bonferroni correction. Results: While the number of errors and correct responses were similar between the groups, the reaction time for correct responses was more in the depression group in comparison to healthy individuals (t = -2.39, Conclusion: Our findings indicate that individuals with depression exhibited prolonged reaction times and distinct activation patterns of the frontal cortex compared to healthy individuals. The observed pattern of brain activation for congruent and incongruent tasks among both healthy and depressed individuals aligns with the findings of the prior studies, emphasizing the utility of fNIRS as a valuable instrument for assessing brain activity.
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