Evidence map›Paper›PMID 39790297›Full record

ArticleOman medical journal2024

Active and Passive Smoking as Catalysts for Cognitive Impairment in Rural Indonesia: A Population-based Study.

Faizal Muhammad, Afifah Syifaul Ummah, Farida Aisyah, Rivan Danuaji, Diah Kurnia Mirawati, Subandi Subandi, Baarid Luqman Hamidi, Ervina Arta Jayanti Hutabarat, Reviono Reviono, Yulie Erida Nur Rahmawati and 1 more

Abstract read
In one paragraph

Article in Oman medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Memory under siege: the cognitive costs of smoking and vaping.Brain, behavior, & immunity - health · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Faizal MuhammadNeurology Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Afifah Syifaul UmmahMedical Clerkship of General Practitioner, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Farida AisyahMedical Clerkship of General Practitioner, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Rivan DanuajiNeurology Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Diah Kurnia MirawatiNeurology Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Subandi SubandiNeurology Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Baarid Luqman HamidiNeurology Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Ervina Arta Jayanti HutabaratNeurology Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Reviono RevionoPulmonology and Respiratory Medicine Department, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia.
Yulie Erida Nur RahmawatiBalai Besar Kesehatan Paru Masyarakat, Ministry of Health of the Republic of Indonesia, Bandung, Indonesia.
Isa RidwanOrthopedics and Traumatology Department, RSUD Kesehatan Kerja, Bandung, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Research indicates that active smokers are at risk of cognitive impairment. However, the correlation between chronic passive smoking and the risk of cognitive impairment remains underexplored. This study aimed to determine the association between smoking, passive smoking, and cognitive impairment and examined the dose-response effect. Methods: This population-based two-year survey was conducted in four rural public health centers from 2021 to 2023 in Central Java, Indonesia, each center caters to approximately 30 000 people. The participants were selected using simple random sampling from the health center visitors aged 30-60 years. Smoking and passive smoking were determined by self-assessment. Mini-Mental State Examination was used to evaluate cognitive impairment. The potential impact of confounding variables such as lifestyle, sociodemographic factors, and chronic diseases were considered and excluded during statistical analysis. Results: The participants were 409 individuals aged 30-60 years. The majority were men (264; 64.5%). Among them, 308 (75.3%) were active smokers, 271 (66.3%) were passive smokers, and 138 (33.7%) were not exposed to tobacco smoke. There was a significant relationship between cognitive impairment and increasing pack years of active smoking. The highest and most significant risk was observed in those who smoked ≥ 20 pack-years with an adjusted odds ratio (aOR) of 1.61 and 95% CI: 0.98-2.31. Passive smokers had a slightly lower risk of cognitive impairment than those who did not smoke and never smoked (aOR = 2.01; 95% CI: 1.37-2.70). They were comparable with OR of 10-19 pack-years total exposure to active smoking (aOR = 1.86; 95% CI: 1.24-2.42). Conclusions: There was a dose-response relationship between smoking and cognitive impairment with a significant effect on ≥ 20 pack-years of exposure. Passive smoking also indicated a significant risk of cognitive impairment equivalent to an estimated 10-19 pack-years of active smoking.

Indexed as

Cognitive ImpairmentsDementiaEpidemiologyIndonesiaNeurodegenerative DiseasesSmoking

Identifiers

PMID39790297
PMCPMC11711741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.