Evidence map›Paper›PMID 39790222›Full record

ArticleJournal of cancer prevention2024

Identification of Translocon-associated Protein Delta as An Oncogene in Human Colorectal Cancer Cells.

Darshika Amarakoon, Wu-Joo Lee, Jing Peng, Seong-Ho Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer prevention, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Darshika AmarakoonDepartment of Nutrition and Food Science, College of Agriculture and Natural Resources, University of Maryland, College Park, MD, USA.ORCID https://orcid.org/0000-0003-3651-0435
Wu-Joo LeeDepartment of Nutrition and Food Science, College of Agriculture and Natural Resources, University of Maryland, College Park, MD, USA.ORCID https://orcid.org/0009-0009-5641-9680
Jing PengDepartment of Nutrition and Food Science, College of Agriculture and Natural Resources, University of Maryland, College Park, MD, USA.ORCID https://orcid.org/0009-0006-8296-2052
Seong-Ho LeeDepartment of Nutrition and Food Science, College of Agriculture and Natural Resources, University of Maryland, College Park, MD, USA.ORCID https://orcid.org/0000-0001-5876-1396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying the roles of genes in cancer is critical in discovering potential genetic therapies for cancer care. Translocon-associated protein delta (TRAPδ), also known as signal sequence receptor 4 (SSR4), is a constituent unit in the TRAP/SSR complex that resides in the endoplasmic reticulum and plays a key role in transporting newly synthesized proteins into the endoplasmic reticulumn. However, its biological role in disease development remains unknown to date. This is the first study to identify the role of TRAPδ/SSR4 in colorectal cancer cells in vitro. Upon successful transient knockdown of

Indexed as

Colorectal cancerEndoplasmic reticulumOncogeneSignal sequence receptor 4Translocon-associated protein delta

Identifiers

PMID39790222
PMCPMC11706732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.