Evidence map›Paper›PMID 39790162›Full record

ArticleAnnals of thoracic surgery short reports2024

Rescuing the Right Ventricle: Mechanical Support After Pediatric Heart Transplantation.

Amee M Bigelow, Catherine Kapcar, Eric Lloyd, Lydia K Wright, Benjamin A Blais, Jordan Voss, Ashley B Walczak, Matthew Deitemeyer, Vicky Duffy, Deipanjan Nandi and 1 more

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amee M BigelowDepartment of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Catherine KapcarDepartment of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Eric LloydDepartment of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Lydia K WrightDepartment of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Benjamin A BlaisDepartment of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Jordan VossDepartment of Cardiothoracic Surgery and Perfusion Services, The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.
Ashley B WalczakDepartment of Cardiothoracic Surgery and Perfusion Services, The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.
Matthew DeitemeyerDepartment of Cardiothoracic Surgery and Perfusion Services, The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.
Vicky DuffyDepartment of Cardiothoracic Surgery and Perfusion Services, The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.
Deipanjan NandiDepartment of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Patrick I McConnellDepartment of Cardiothoracic Surgery and Perfusion Services, The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Right ventricular (RV) failure after heart transplantation (HT) is common in those with pretransplantation elevated pulmonary vascular resistance (PVR). Mechanical circulatory support has been used as a bridge to recovery, with mixed outcomes. We describe a patient with failed single-ventricle palliation in whom severe RV failure developed after HT. We review the current literature and outline our post-HT strategy. Methods: An infant with trisomy 21, severely unbalanced right dominant atrioventricular septal defect, and hypoplastic aortic arch was palliated with a hybrid procedure. At 6 months of age, cardiac catheterization measured PVR index of 5.47 Wood units × m Results: Failure of medical therapy in RV failure after HT requires escalation to mechanical circulatory support. We review the literature on RV failure and support after HT. We also describe a novel cannulation strategy to provide a reliable way to directly reduce RV afterload, to allow physiologic training of the right ventricle to a higher PVR, and to maintain normal left ventricular coupling and loading. Conclusions: In pediatric patients with elevated PVR undergoing HT, advanced therapies can be used effectively to treat acute RV failure. Unique cannulation strategies may play a role in improving survival of similar patients.

Identifiers

PMID39790162
PMCPMC11708400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.