Evidence map›Paper›PMID 39790158›Full record

ArticleAnnals of thoracic surgery short reports2024

Quantifying Additional Procedures in Functionally Single-Ventricle Disease: A National Cohort Study.

Qi Huang, Deborah Ridout, Victor Tsang, Nigel E Drury, Timothy J Jones, Hannah Bellsham-Revell, Elena Hadjicosta, Anna N Seale, Chetan Mehta, Christina Pagel and 4 more

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qi HuangClinical Operational Research Unit, Department of Mathematics, University College London, London, United Kingdom.
Deborah RidoutPopulation, Policy and Practice Programme, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Victor TsangGreat Ormond Street Hospital Biomedical Research Centre and Institute of Cardiovascular Science, University College London, London, United Kingdom.
Nigel E DruryDepartment of Paediatric Cardiology and Cardiac Surgery, Birmingham Children's Hospital, Birmingham, United Kingdom.
Timothy J JonesDepartment of Paediatric Cardiology and Cardiac Surgery, Birmingham Children's Hospital, Birmingham, United Kingdom.
Hannah Bellsham-RevellDepartment of Paediatric Cardiology, Evelina London Children's Hospital, London, United Kingdom.
Elena HadjicostaClinical Operational Research Unit, Department of Mathematics, University College London, London, United Kingdom.
Anna N SealeDepartment of Paediatric Cardiology and Cardiac Surgery, Birmingham Children's Hospital, Birmingham, United Kingdom.
Chetan MehtaDepartment of Paediatric Cardiology and Cardiac Surgery, Birmingham Children's Hospital, Birmingham, United Kingdom.
Christina PagelClinical Operational Research Unit, Department of Mathematics, University College London, London, United Kingdom.
Sonya CroweClinical Operational Research Unit, Department of Mathematics, University College London, London, United Kingdom.
Ferran Espuny-PujolClinical Operational Research Unit, Department of Mathematics, University College London, London, United Kingdom.
Rodney C G FranklinDepartment of Paediatric Cardiology, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.
Kate L BrownGreat Ormond Street Hospital Biomedical Research Centre and Institute of Cardiovascular Science, University College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Given their importance as a metric for health care evaluation, this study's aim was to evaluate the rates of surgical and catheter reinterventions for children with functionally single-ventricle (f-SV) congenital heart disease (CHD) undergoing staged palliation. Methods: We undertook a retrospective cohort study of children born with f-SV CHD between 2000 and 2018 in England and Wales, using the national registry, with survival ascertained in 2020. Competing risk analysis was used to describe the incidence of additional procedures that occurred first, during follow-up, accounting for competing events of death or transplantation. Results: Of 56,039 patients who received an intervention for CHD, 3307 (5.9%) had f-SV. The largest diagnostic subcategories were hypoplastic left heart syndrome (1266 [38.3%]), tricuspid atresia (448 [13.5%]), and double-inlet left ventricle (328 [9.9%]). During a median follow-up of 5.4 (interquartile range, 0.8-10.8) years, 921 (27.9%) patients had at least 1 additional interstage surgery and 1293 (39.1%) had at least 1 additional interstage catheter intervention. The cumulative incidence of additional surgery at 6 months after stage 1 was 17.6% (95% CI, 16.2%-19.0%); at 2 years after stage 2, 8.3% (7.2%-9.5%); and at 5 years after stage 3, 8.4% (7.0%-9.9%). The cumulative incidence of additional catheter at 6 months after stage 1 was 18.0% (16.6%-19.4%); at 2 years after stage 2, 14.7% (13.3%-16.2%); and at 5 years after stage 3, 23.7% (21.5%-26.0%). Conclusions: It is important to quantify additional procedures for children with f-SV disease to inform parents and health professionals, potentially facilitating the development of interventions that aim to reduce these important adverse outcomes.

Identifiers

PMID39790158
PMCPMC11708582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.