Evidence map›Paper›PMID 39790073›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

Neonatal acute liver failure cases with echovirus 11 infections, Japan, August to November 2024.

Tatsuki Ikuse, Toshihiro Matsui, Kensuke Shoji, Naoko Kono, Masaki Yamada, Chikara Ogimi, Chika Takahashi, Takanori Funaki, Kentaro Ide, Shotaro Matsumoto and 8 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Enterovirus infections in children.Pediatric investigation · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Tatsuki IkuseDivision of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Toshihiro MatsuiDivision of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Kensuke ShojiDivision of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Naoko KonoDivision of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Masaki YamadaDivision of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Chikara OgimiDivision of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Chika TakahashiInfectious Disease Control Division, Setagaya Public Health Center, Tokyo, Japan.
Takanori FunakiCenter for Research Planning and Coordination, National Institute of Infectious Diseases, Tokyo, Japan.
Kentaro IdeCritical Care Medicine, National Center for Child Health and Development, Tokyo, Japan.
Shotaro MatsumotoCritical Care Medicine, National Center for Child Health and Development, Tokyo, Japan.
Reiko ItoDepartment of General Paediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
Rinshu ShimabukuroDepartment of General Paediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
Yoshihiro GochoChildren's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Itaru HayakawaDivision of Neurology, National Center for Child Health and Development, Tokyo, Japan.
Takashi IshikawaDivision of Immunology, National Center for Child Health and Development, Tokyo, Japan.
Seisuke SakamotoOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Mureo KasaharaOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Takashi IgarashiPresident's office, National Center for Child Health and Development, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2022-23, several European countries reported paediatric acute liver failure (ALF) with enterovirus infection. In August-November 2024, three neonatal cases of ALF with echovirus 11 (E11) were reported in Tokyo, Japan. All neonates developed irreversible multiple-organ failure and died. The E11 strain belonged to the new lineage 1, which was the same as strains isolated from neonatal ALF cases in Europe in 2022-23.

Indexed as

Echovirus InfectionsEnterovirus B, HumanLiver Failure, AcuteFemaleHumansInfant, NewbornJapanMalePhylogenyacute liver failureechovirus 11enterovirushepatitisneonate

Identifiers

PMID39790073
PMCPMC11719806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.