Evidence map›Paper›PMID 39789976›Full record

ArticleFuture oncology (London, England)2025

Treatment of metastatic urothelial carcinoma in the United Kingdom, France, Germany, Italy, and Spain.

Ahmet Hasaligil, Vicki Munro, Torsten Strunz-McKendry, Jing Wang-Silvanto, Neil Milloy, Mia Unsworth, Maria De Santis

Abstract read
In one paragraph

Article in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmet HasaligilAstellas Pharma Europe Ltd., Addlestone, UK.
Vicki MunroAstellas Pharma Europe Ltd., Addlestone, UK.
Torsten Strunz-McKendryAstellas Pharma Europe Ltd., Addlestone, UK.ORCID 0000-0001-6032-8794
Jing Wang-SilvantoAstellas Pharma Europe Ltd., Addlestone, UK.
Neil MilloyAdelphi Real World, Bollington, UK.
Mia UnsworthAdelphi Real World, Bollington, UK.
Maria De SantisDepartment of Urology, Charité Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe treatment landscape of metastatic urothelial carcinoma (mUC) has evolved with the emergence of programmed cell death protein 1/ligand 1 (PD-1/L1) inhibitors. This study assessed mUC treatment patterns in Europe.

methodsData were derived from the Adelphi mUC Disease Specific Programme™ (November 2020 to April 2021), a large, cross-sectional, patient record-based survey of physicians in France, Germany, Italy, Spain, and the United Kingdom. Patient characteristics, treatment patterns across lines of therapy, and treatment durations were assessed.

resultsPhysicians (

conclusionsMost patients received platinum-based chemotherapy in first-line, followed by a PD-1/L1 inhibitor. A substantial proportion received best supportive care after second-line. Findings indicate unmet need for the later-line treatment of mUC and provide important context for the emergence of novel therapies.

Indexed as

Antineoplastic AgentsAntineoplastic ProtocolsCarcinomaImmune Checkpoint InhibitorsUrinary Bladder NeoplasmsCross-Sectional StudiesEuropeHumansNeoplasm MetastasisAntineoplastic AgentsImmune Checkpoint Inhibitorsbest supportive carechemotherapyenfortumab vedotinerdafitinibEuropeimmune checkpoint inhibitorsMetastatic urothelial carcinomareal-world evidence

Identifiers

PMID39789976
PMCPMC11845109

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.