Evidence map›Paper›PMID 39789503›Full record

ArticleBMC ophthalmology2025

An improvement in visual acuity accompanied by the development of RPE tear: a case report.

Xinyu Liu, Shulin Liu, Zhiyan Xu, Youxin Chen

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinyu LiuDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
Shulin LiuChongqing Key Laboratory of Ophthalmology, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing Eye Institute, Chongqing, People's Republic of China.
Zhiyan XuDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
Youxin ChenDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan, Dongcheng District, Beijing, 100730, China. chenyx@pumch.cn.

Funding

National Natural Science Foundation of China 82271112
6 · The paper itself

Abstract

backgroundRetinal pigment epithelium (RPE) tear is a well-known complication of RPE detachment and is typically associated with significant visual acuity decline. However, in this case, despite the occurrence of an RPE tear there was an unexpected improvement in visual acuity. CASE PRESENTATION: A 68-year-old male presented with blurred vision in his right eye of a month's duration. Pachychoroid neovasculopathy was diagnosed. After monthly anti-vascular endothelial growth factor injections over a three months period. the choroidal neovascular membrane gradually diminished. While the pigment epithelial detachment expanded and the subretinal fluid increased. This was accompanied by deterioration in the visual acuity of the patient. The anti-VEGF treatment was discontinued, expectant management was adopted. Three months later, a retinal pigment epithelium tear was observed near the fovea, unexpectedly accompanied by complete resolution of the subretinal fluid, partial reattachment of the RPE detachment, and a significant improvement in visual acuity.

conclusionsThis case presents a rare instance of significant improvement in visual acuity and anatomical reconstruction of macular structure following the development of a retinal pigment epithelial (RPE) tear in a patient with pachychoroid neovasculopathy. We suggest that the fovea-sparing nature of the RPE tear in our case and the resulting "incision and drainage" effect may explain this unexpected outcome.

Indexed as

Retinal PerforationsTomography, Optical CoherenceVisual AcuityAgedChoroidal NeovascularizationFluorescein AngiographyHumansMaleRetinal Pigment EpitheliumPachychoroid neovasculopathyRetinal pigment epithelial detachmentRetinal pigment epithelium tear

Identifiers

PMID39789503
PMCPMC11715563

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