Evidence map›Paper›PMID 39789363›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Tie or do not tie: comparing knot tying hemostasis in tonsillectomy with other methods of hemostasis. A systematic review and meta-analysis.

Euan C E Ó Mathúna, Mel Corbett, Lisa O Byrne, Moustafa Aly, Matthew G Davey, Seng-Guan Khoo

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Euan C E Ó MathúnaAcademic Department of Otolaryngology-Head and Neck Surgery, Royal College of Surgeons Ireland, 123 St. Stephen's Green, Dublin 2, D02 YN77, Ireland. euanomathuna@gmail.com.ORCID http://orcid.org/0000-0003-0788-2416
Mel CorbettAcademic Department of Otolaryngology-Head and Neck Surgery, Royal College of Surgeons Ireland, 123 St. Stephen's Green, Dublin 2, D02 YN77, Ireland.ORCID http://orcid.org/0000-0001-5320-1015
Lisa O ByrneAcademic Department of Otolaryngology-Head and Neck Surgery, Royal College of Surgeons Ireland, 123 St. Stephen's Green, Dublin 2, D02 YN77, Ireland.
Moustafa AlyAcademic Department of Otorhynolaryngolgy, University Hospital Galway, Newcastle Road, Galway, Ireland.ORCID http://orcid.org/0009-0001-6725-4764
Matthew G DaveyAcademic Department of Otolaryngology-Head and Neck Surgery, Royal College of Surgeons Ireland, 123 St. Stephen's Green, Dublin 2, D02 YN77, Ireland.
Seng-Guan KhooAcademic Department of Otolaryngology-Head and Neck Surgery, Royal College of Surgeons Ireland, 123 St. Stephen's Green, Dublin 2, D02 YN77, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis meta-analysis sought to compare knot tying against other methods of haemostasis in terms of post-operative haemorrhage, intraoperative blood loss and tonsillectomy time.

methodsTwo independent reviewers performed a literature search according to PRISMA guidelines. Three databases were consulted, Pubmed, Google Scholar and Embase. Studies comparing knot tying with any other form of tonsillectomy haemostasis were included.

resultsSix studies met inclusion criteria for meta-analysis, comprising 1764 patients. When comparing knot tying with other forms of haemostasis there was no significant difference in terms of post-operative haemorrhage rates (odds ratio) (OR: 2.31, 95% CI 0.37 to 14.28, P = 0.37, I

conclusionsTonsillectomy is one of the oldest operations and traditional tonsil surgery has preceded the advent of evidence-based practice. Tie ligation of bleeding vessels is an effective method of securing intraoperative haemostasis and a skill all surgeons should be competent in. Our systematic review and meta-analysis found no evidence to support knot tying of tonsils to prevent post tonsillectomy bleeding compared to any haemostatic intervention during any method of tonsillectomy.

Indexed as

Blood Loss, SurgicalHemostasis, SurgicalPostoperative HemorrhageSuture TechniquesTonsillectomyHumansOperative TimeHaemostasisKnot tyingTonsillectomy

Identifiers

PMID39789363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.