Evidence map›Paper›PMID 39789321›Full record

ArticleScientific reports2025

Trends in global and regional incidence and prevalence of hypertensive disordersin pregnancy (1990-2021): an age-period-cohort analysis.

Shu Sun, Wangshu Li, Xu Zhang, Aziz Ur Rehman Aziz, Na Zhang

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Shu Sun *China Key Laboratory for Early Diagnosis and Biotherapy of Malignant Tumors in Children and Women, Dalian Women and Children's Medical Group, Street No. 154, Zhong Shan Road, Xigang District, Dalian, 116012, Liaoning Province, China.
Wangshu Li *China Key Laboratory for Early Diagnosis and Biotherapy of Malignant Tumors in Children and Women, Dalian Women and Children's Medical Group, Street No. 154, Zhong Shan Road, Xigang District, Dalian, 116012, Liaoning Province, China.
Xu ZhangThe Second Affiliated Hospital of Harbin Medical University, Harbin, 151801, Heilongjiang, China.
Aziz Ur Rehman AzizChina Key Laboratory for Early Diagnosis and Biotherapy of Malignant Tumors in Children and Women, Dalian Women and Children's Medical Group, Street No. 154, Zhong Shan Road, Xigang District, Dalian, 116012, Liaoning Province, China. azizjatoi@hotmail.com.
Na ZhangDepartment of Gynecology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, 750002, Ningxia, China. zhangna19830203@163.com.

Funding

Dalian Life and Health Guidance Program Project-Directive 2023 243Dalian Outstanding Young Science and Technology Talent Program 2023RY020Ningxia Science and Technology Benefiting the People Project 2022CMG03020
6 · The paper itself

Abstract

Hypertensive disorders of pregnancy (HDP) are significant global health issues. This study utilized data from the Global Burden of Disease Study 2021 to analyze trends in incidence, prevalence, and Disability-Adjusted Life Years (DALY) associated with HDP across 204 countries from 1990 to 2021. The analysis employed estimated annual percentage changes and an age-period-cohort model, stratifying data by age, year, geographical region, and sociodemographic index (SDI). Statistical analyses and visualizations were conducted using R. Between 1990 and 2021, global HDP incidence rose from 31.33 million to 36.10 million cases (15.24%), while prevalence surged from 6.15 million to 36.10 million cases (487%). Despite the increase in absolute cases, the age-standardized rates for incidence and prevalence exhibited only modest changes, with incidence up by 15.23% and prevalence slightly declining. Regions with high and high-middle SDI showed decreasing trends, whereas middle, low-middle, and low SDI regions faced rising trends. DALYs linked to HDP decreased from 6.96 million in 1990 to 4.94 million in 2021, with significant reductions in high SDI areas. Projections indicate a continued decrease in the global burden of HDP by 2040. The study concludes that continued efforts in prenatal care and health education are vital, particularly in low SDI regions, to mitigate the impact of HDP.

Indexed as

Global HealthHypertension, Pregnancy-InducedAdultCohort StudiesDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansIncidenceMiddle AgedPregnancyPrevalenceYoung AdultBurden of diseaseHypertensive disorders of pregnancySociodemographic index

Identifiers

PMID39789321
PMCPMC11718268

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.