SynthesisMedical & biological engineering & computing2025
A systematic review of the blockchain application in healthcare research domain: toward a unified conceptual model.
Synthesis in Medical & biological engineering & computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Blockchain technology for secure and efficient nephrology data management.Clinical kidney journal · 2026Review
- Mapping Characteristics, Applications, and Implementation Challenges of Virtual Communities in Cancer Care: NASSS Framework-Informed Scoping Review.Journal of medical Internet research · 2025Article
- Blockchain-enabled quality by design system for clinical trials.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, research on blockchain applications in the healthcare research domain has attracted increasing attention due to its strong potential. However, the existing literature reveals limited studies on defining use cases of blockchain in clinical research, categorizing and comparing available studies. Therefore, this study aims to explore the significant potential and use cases of blockchain in clinical research through a comprehensive systematic literature review (SLR). To thoroughly investigate all aspects of the subject, we analyzed primary studies based on research questions (RQs) and developed a unified conceptual model using step-based model creation. Studies from 2015 to 2023 were reviewed, and 34 primary studies were comprehensively analyzed by using the PICO template. In our findings, privacy emerged as the most frequently cited requirement in clinical research. The most mentioned use cases for blockchain are ensuring data immutability and security. A significant issue identified beyond the common blockchain limitations of capacity and scalability is the lack of standards for compliance with legal frameworks like GDPR and HIPAA. After all these efforts, we developed a conceptual model, which, to our best knowledge, is the first in the literature to support software developers and clinical researchers in developing and using blockchain-based research platforms efficiently.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.