Observational studyCardiovascular and interventional radiology2025
Ultrasound-guided Transperineal Prostate Thermal Ablation (TPTA) for Benign Prostatic Hyperplasia: Feasibility of an Outpatient Procedure using Radiofrequency Ablation.
Observational study in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Free-Hand Moving-Shot Technique for Ultrasound-Guided Transperineal Prostate Ablation: A Technical Note.Cardiovascular and interventional radiology · 2026Article
- Laser or Radiofrequency for BPH? Moving Beyond Energy Competition.Cardiovascular and interventional radiology · 2026Article
- Two-Year Durability After Image-Guided Urethra-Sparing Transperineal Radiofrequency Ablation for Benign Prostatic Hyperplasia: Follow-Up Update of a Prospective Cohort.Cardiovascular and interventional radiology · 2026Article
- Percutaneous Radiofrequency Ablation of the Prostate for BPH: A New Frontier to be Explored by Interventional Radiologists.Cardiovascular and interventional radiology · 2026Article
- Freehand Ultrasound-Guided Transperineal Microwave Ablation for Benign Prostatic Hyperplasia: A Novel Application.Cureus · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the feasibility, safety, and short-term (3-month) results of transperineal prostate thermal ablation (TPTA) as a minimally invasive outpatient treatment for benign prostatic hyperplasia (BPH). MATERIALS AND
methodsA prospective nonrandomized study of 25 patients with lower urinary tract symptoms secondary to BPH seeking care at 2 interventional radiology centers between March and July 2024. TPTA was performed using a 17G radiofrequency needle with a 10-mm active tip under unconscious sedation combined with bilateral perineal and periprostatic nerve blocks. The primary outcome measure was technical success, defined as successful bilateral ablation of the prostate transition zone. Secondary outcome measures included changes of international prostate symptom score (IPSS), quality of life (QoL), prostate volume, intravesical prostatic protrusion (IPP), prostate-specific antigen (PSA), post-void residual volume (PVR), maximum urinary flow rate (Qmax), and need for BPH medical therapy at 3 months relative to baseline.
resultsAll procedures were technically successful (100%). The median patient age was 69.4 years (IQR 54-74), and all were discharged within 3 h of the end of the procedure. Sixteen patients (64.0%) were discharged without a urinary catheter, and 6 patients (24.0%) reported mild complications. At 3-month follow-up, there were significant reductions in IPSS (79.1%), QoL score (70.3%), prostate volume (36.9%), IPP (70.8%), PSA (54.7%), and PVR (51.1%), whereas Qmax increased significantly (102.3%). Twenty-four patients (96.0%) reported discontinuation of medical therapy after TPTA.
conclusionUltrasound-guided TPTA using radiofrequency ablation is feasible and safe in the outpatient setting, with significant clinical improvements after 3 months of the procedure. LEVEL OF EVIDENCE: Level 3 [non-randomized prospective cohort study].
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