Observational studyScientific reports2025
Incidence and risk factors of postoperative delirium in elderly surgical patients 2023.
Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 25 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Perioperative Use of Dexmedetomidine-esketamine Combination and Transcranial Direct Current Stimulation for Prevention of Neurocognitive Complications in Older Patients After Non-cardiac Surgery: a 2×2 Factorial Trial
Long-term Follow-up of Perioperative Dexmedetomidine-esketamine Combination and Transcranial Direct Current Stimulation for Prevention of Neurocognitive Complications in Older Patients After Non-cardiac Surgery
Impact of Perioperative Transcranial Photobiomodulation on Delayed Neurocognitive Recovery in Older Patients After Surgery: a Randomized, Double-blind, Pseudo-modulation-controlled Preliminary Clinical Trial
Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The delirium dichotomy of remimazolam: a differential risk profile for emergence delirium versus postoperative delirium in surgical patients: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Association between the geriatric nutritional risk index and postoperative delirium: a meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Factors associated with postoperative delirium in patients undergoing oral and maxillofacial surgery: a meta-analysis of observational study.Frontiers in medicine · 2026Pooled it
- Association of remimazolam with delirium and cognitive function in elderly patients undergoing general anesthesia or procedural sedation: a meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Perioperative dexmedetomidine nasal spray improves postoperative sleep in patients undergoing thoracoscopic lung surgery: a prospective, randomized controlled trial.BMC anesthesiology · 2026Trial
- Effect of Ciprofol on Postoperative Cognitive Function in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial.Drug design, development and therapy · 2025Trial
- Gut microbiota and blood biomarkers as correlating factors in patients with postoperative delirium: analysis of three prospective observational studies.Molecular psychiatry · 2026Article
- Article
- Electroencephalographic Monitoring in the Recovery Room for Identification of Patients at Risk for Postoperative Delirium.Anesthesiology · 2026Observational
- Associations of postoperative delirium with perioperative frailty worsening and their combined effect on 1-year mortality in older surgical patients: a prospective cohort study.European geriatric medicine · 2026Article
- Preoperative Workup by a Dedicated Geriatric Surgery Service Improves Outcomes in Elderly Patients Undergoing Pancreaticoduodenectomy.Journal of surgical oncology · 2026Article
- Pharmacological Management of Delirium in Older Adults in the Emergency Department: Clinical Outcomes.Diseases (Basel, Switzerland) · 2026Article
- Cognitive Impact of Colorectal Cancer Surgery in Elderly Patients: A Narrative Review.Cancers · 2026Review
- Comment on "Effect of remimazolam on postoperative delirium in elderly patients undergoing major abdominal surgery: a randomized controlled trial".International journal of surgery (London, England) · 2026Article
- Clinical Relevance of Preoperative Lymphocyte-to-Monocyte Ratio in Predicting Postoperative Delirium Across Frailty Status in Older Surgical Patients.Clinical interventions in aging · 2026Article
- Incidence and Risk Factors for Postoperative Delirium Following Robotic and Video-Assisted Pulmonary Lobectomy: Analysis of the Nationwide Inpatient Sample, 2005-2020.Clinical epidemiology · 2026Article
- Shared molecular mechanisms between colorectal cancer and cardiovascular disease drive perioperative neurological vulnerability.Frontiers in genetics · 2026Article
- Recent advances in postoperative delirium in elderly patients: pathophysiological mechanisms, risk prediction, and therapeutic strategies.Frontiers in neuroscience · 2026Review
- Postoperative delirium in elderly orthopedic patients: a narrative review of prevention and multidisciplinary nursing interventions.Frontiers in psychiatry · 2026Review
- A nomogram and risk stratification for predicting subsyndromal delirium in elderly patients in a post-anaesthesia care unit: A prospective cohort study.International journal of nursing studies advances · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative delirium has the potential to impact individuals of all age groups, with a significant emphasis on the elderly population. Its presence leads to an increase in surgical morbidity and mortality rates, as well as a notable prolongation of hospital stays. However, there is a lack of research regarding the prevalence, risk factors, and implications of postoperative delirium in developing nations like Ethiopia, which affects both patients and healthcare institutions. An observational study was conducted at hospitals in the South Gondar Zone to diagnose postoperative delirium in the Post-Anesthesia Care Unit (PACU) using the Nursing Delirium Screening Scale. Both bivariable and multivariable logistic regression techniques were employed to analyze the association between independent factors and postoperative delirium. The strength of the association was indicated by the odds ratio with a 95% confidence interval (CI). Any p-values below 0.05 were considered statistically significant. The incidence of postoperative delirium was determined to be 41%. In the multivariate logistic regression analysis, several factors were identified as significantly associated with postoperative delirium. These factors include an age of 75 or older (AOR, 11.24; 95% CI, 4.74-26.65), ASA-PS IV (AOR, 3.25; 95% CI, 1.81-5.85), severe functional impairment of activities of daily living (AOR, 3.29; 95% CI, 1.06-10.20), premedication with benzodiazepine (AOR, 4.61; 95% CI, 2.48-8.57), intraoperative estimated blood loss exceeding 1000 ml (AOR, 2.74; 95% CI, 1.50-4.98), and intraoperative ketamine use (AOR, 3.84; 95% CI, 2.21-6.68). Additionally, postoperative delirium was found to significantly prolong the duration of stay in the post-anesthesia care unit (PACU) and the length of hospital stay (p-value < 0.05). Patients aged 75 or older, ASA-PS IV, experiencing severe functional impairment of ADL, patients premedicated with benzodiazepine, patients with intraoperative estimated blood loss exceeding 1000 ml, and intraoperative ketamine use were identified as risk factors for post-operative delirium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.