ArticleBMJ open2025
Protocol for the development of a guideline on post-extubation respiratory support for mechanically ventilated patients in the ICU.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
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Abstract
Prophylactic respiratory support for patients after extubation is effective in improving their outcomes and prognosis. However, the optimal post-extubation respiratory support for different populations and disease types of mechanically ventilated patients remains controversial, and there is a lack of detailed, multidisciplinary, evidence-based recommendations for clinical application. METHODS AND ANALYSIS: This protocol strictly follows the development process outlined in the WHO Handbook for Guideline Development and Guidelines 2.0, as well as the guidelines for the development of relevant methodological standards. Key steps in developing the guideline include: (1) establishing the guideline working groups, (2) defining the scope of guideline application, (3) selecting the priority clinical questions, (4) retrieving and screening evidence, (5) grading the quality of evidence, (6) forming recommendations and (7) conducting an external review. ETHICS AND DISSEMINATION: Ethical approval has been granted by Changzhi People's Hospital (2023K023). Findings from this study will be disseminated through peer-reviewed publications. GUIDELINE REGISTRATION: PREPARE-2023CN418.
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