Evidence map›Paper›PMID 39788509›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Construction and biological function of

Kaijuan Wu, Jing Xie, Xiaohua Liu, Dongqian Yang, Yixiao Wang, Wanchen Zhao, Xiaomin Shang, Liping Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kaijuan WuDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013. wkjcsu@csu.edu.cn.
Jing XieDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013.
Xiaohua LiuDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013.
Dongqian YangDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013.
Yixiao WangDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013.
Wanchen ZhaoXiangya School of Medicine, Central South University, Changsha 410013, China.
Xiaomin ShangDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013. xmshang@csu.edu.cn.
Liping JiangDepartment of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013. jiangliping@csu.edu.cn.

Funding

the Innovation Training Program of Central South University 20240026020055the National Natural Science Foundation of China 32170510
6 · The paper itself

Abstract

objectivesToxoplasmosis is a zoonotic parasitic disease caused by

methodsUsing CRISPR/Cas9 technology, a specific single-guide RNA (sgRNA) for the target gene was designed and linked to a recombinant plasmid. Homologous fragments were fused with a pyrimethamine resistance gene for selection purposes. The recombinant plasmid and the homologous fragments were electroporated into

resultsThe

conclusionsThe

Indexed as

Gene Knockout TechniquesProtozoan ProteinsToxoplasmaAnimalsCRISPR-Cas SystemsPlasmidsVirulence FactorsProtozoan ProteinsVirulence Factorsfunctional enrichment analysisgene knockoutrhoptry protein 41Toxoplasma gondii

Identifiers

PMID39788509
PMCPMC11628218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.