Evidence map›Paper›PMID 39788491›Full record

ReviewZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Childhood obesity and central precocious puberty.

Ruonan Li, Xin Shang, Tenglin Zhang, Shuxun Yan

Abstract readReview
In one paragraph

Review in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Performance of a prompt engineering method for extracting individual risk factors of precocious puberty from electronic medical records].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruonan LiSecond Ward of Endocrinology Department, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000. liruonan199308@163.com.
Xin ShangSecond Ward of Endocrinology Department, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000.
Tenglin ZhangSecond Ward of Endocrinology Department, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000.
Shuxun YanSecond Ward of Endocrinology Department, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000. ysx982001@163.com.

Funding

the Henan Province Science and Technology Research Project 232102310431
6 · The paper itself

Abstract

Central precocious puberty (CPP) is an endocrine disorder in children caused by the early activation of the hypothalamic-pituitary-gonadal axis (HPGA), leading to elevated gonadotropin-releasing hormone (GnRH), which triggers the development of gonads and the secretion of sex hormones. This eventually results in the development of internal and external genitalia and secondary sexual characteristics. CPP significantly affects the physical and mental health of children and may increase the risk of various adult diseases. The influencing factors and mechanisms of CPP are a central focus of research, and its prevention and treatment remain challenging. Childhood obesity is an important risk factor for CPP, with a complex relationship influenced by endocrine-disrupting chemicals, genetic factors, and epigenetic regulation. The link between the two is primarily related to the regulation of HPGA function by nutritional and metabolic signals. Exploring the relationship between childhood obesity and CPP, along with the potential mechanisms by which obesity induces CPP, can provide theoretical references for identifying new therapeutic targets.

Indexed as

Pediatric ObesityPuberty, PrecociousChildEndocrine DisruptorsFemaleGonadotropin-Releasing HormoneHumansHypothalamo-Hypophyseal SystemMaleRisk FactorsEndocrine DisruptorsGonadotropin-Releasing Hormoneadipokinescentral precocious pubertychildhood obesityhypothalamic-pituitary-gonad axis

Identifiers

PMID39788491
PMCPMC11495981

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.