ArticleNoise & health
Effect of Medial Olivocochlear Efferents on Speech Discrimination in Noise in Multiple Sclerosis.
Article in Noise & health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07136311 (Otoacoustics Emissions Contralateral Supression Test), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Otoacoustics Emissions Contralateral Supression Test
Who cites it
1 citing paper in PubMed.
- Medial olivocochlear reflex dysfunction in multiple sclerosis: The influence of brainstem lesion localization and its clinical implications.World journal of clinical cases · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with multiple sclerosis (MS) experience difficulties in understanding speech in noise despite having normal hearing.
aimThis study aimed to determine the relationship between speech discrimination in noise (SDN) and medial olivocochlear reflex levels and to compare MS patients with a control group. MATERIAL AND
methodsSixty participants with normal hearing, comprising 30 MS patients and 30 healthy controls, were included. For both groups, distortion product otoacoustic emissions (DPOAEs) were recorded at frequencies of 1000, 1400, 2000, 2800, 4000, 5600 and 8000 in the presence and absence of contralateral white sound at 65 dB SPL. Speech discrimination tests in the presence and absence of noise, Symbol Digit Modalities Test (SDMT) and Montreal Cognitive Assessment (MoCA) scale were applied to all participants to evaluate their cognitive skills.
resultsIn age- and sex-matched groups, the DPOAE signal-to-noise ratio value was 6.50 ± 1.30 in the right ear at a frequency of 8000 Hz in the control group and 2.40 ± 1.75 in the MS group (P < 0.05). In the comparison of suppression between ears, lower suppression was found at 1400 and 2000 Hz in the left ear and 1000 Hz in the right ear in the MS group (P < 0.05). In the control group, a moderately significant positive correlation existed between right ear SDN scores and left ear suppression values (P < 0.05). The cognitive functions of the MS group were lower in MoCA and SDMT (P < 0.05). Patients who scored less than 21 points in MoCA also had low suppression results (P < 0.05).
conclusionComprehensive evaluations are necessary to uncover the presence of auditory perception disorders, such as noise sensitivity or speech disorders in noise, amongst MS patients.
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