Evidence map›Paper›PMID 39786624›Full record

ArticleTransgenic research2025

NtLPA1 overexpression regulates the growth of tobacco and enhances resistance to blight.

Guiqin Shi, Yanxiao Bu, Lei Chi, Xifeng Zhang, Yuqing Meng, Shijie Zhang, Geng Tian

Abstract read
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In one paragraph

Article in Transgenic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guiqin ShiSchool of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450001, China. guiqinshi@126.com.
Yanxiao BuSchool of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450001, China.
Lei ChiSchool of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450001, China.
Xifeng ZhangShaanxi Tobacco Company Baoji City Company, Baoji, 721000, Shaanxi, China.
Yuqing MengSchool of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450001, China.
Shijie ZhangShaanxi Tobacco Company Baoji City Company, Baoji, 721000, Shaanxi, China.
Geng TianShaanxi Tobacco Company Baoji City Company, Baoji, 721000, Shaanxi, China. 30588187@qq.com.

Funding

Open Project of the Key Laboratory for Monitoring and ComprehensiveManagement of Tobacco Diseases and Pests in the Tobacco Industry KLTPMIMT2023-05Scientific and Technological Projects in Henan Province 242102111029Shaanxi Tobacco Company Technology Project KJ-2023-05
6 · The paper itself

Abstract

The involvement of Loose Plant Architecture 1 (LPA1) in regulating plant growth and leaf angle has been previously demonstrated. However, the fundamental genetic background remains unidentified. To further understand the tissue expression profile of the NtLPA1 gene, an overexpression vector (pBI121-NtLPA1) was developed and employed to modify tobacco using the leaf disc method genetically. Validation confirmed the generation of transgenic tobacco plants with NtLPA1 overexpression. The findings indicated that increased NtLPA1 overexpression substantially decreased plant auxin sensitivity and modulated signal transduction and polar transport, significantly reducing leaf angle, diminished leaf area during early and late growth stages, and shortened root length. In summary, NtLPA1 augmented tobacco resistance to severe shin disease by modulating the expression of disease-associated genes PBZ1, PR1b, and the growth regulator auxin polar transport factor PIN1.

Indexed as

Disease ResistanceGene Expression Regulation, PlantNicotianaPlant DiseasesPlant ProteinsPlants, Genetically ModifiedIndoleacetic AcidsPlant LeavesIndoleacetic AcidsPlant ProteinsLeaf angleNtLPA1OverexpressionTobacco sore shin

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.